Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 10/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21316425 | 0.87 | MEN1 (0.35) | GPR35MAOBMAOAMEN1KMT2A | |
| SCHEMBL31114132 | 0.84 | MAOA (0.40) | GPR35MAOBMAOAMEN1KMT2A | |
| SCHEMBL21316426 | 0.84 | MEN1 (0.34) | GPR35MAOBMAOAMEN1KMT2A | |
| SCHEMBL12038326 | 0.83 | MEN1 (0.33) | GPR35MAOBMAOAMEN1KMT2A | |
| SCHEMBL18712548 | 0.82 | MEN1 (0.35) | GPR35MAOBMAOAMEN1KMT2A | |
| SCHEMBL12038332 | 0.80 | MAOB (0.34) | GPR35MAOBMAOAMEN1KMT2A | |
| SCHEMBL31114267 | 0.80 | GPR35 (0.44) | GPR35MAOBMAOAMEN1KMT2A | |
| SCHEMBL12038299 | 0.79 | MEN1 (0.39) | GPR35MAOBMAOAMEN1KMT2A | |
| SCHEMBL25443859 | 0.79 | GPR35 (0.44) | GPR35MAOBMAOAMEN1KMT2A | |
| SCHEMBL17942944 | 0.78 | MAOB (0.38) | MAOBMAOAALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139550-B2 | Fluorescence dye tagging scheme for mercury quantification and speciation | LOS GATOS RESEARCH (US) | 2015-09-22 | — | — | US | claimed |
| US-20130040393-A1 | FLUORESCENCE DYE TAGGING SCHEME FOR MERCURY QUANTIFICATION AND SPECIATION | LOS GATOS RESEARCH (US) | 2013-02-14 | — | — | US | claimed |
| WO-2022136402-A1 | METHODS AND COMPOSITIONS FOR NUCLEIC ACID SEQUENCING | ILLUMINA CAMBRIDGE LIMITED (GB) | 2022-06-30 | — | — | WO | disclosed |
| US-20220195518-A1 | METHODS AND COMPOSITIONS FOR NUCLEIC ACID SEQUENCING | ILLUMINA CAMBRIDGE LIMITED (GB) | 2022-06-23 | — | — | US | disclosed |
| US-20210285953-A1 | POLYMERIC DYES HAVING A BACKBONE COMPRISING ORGANOPHOSPHATE UNITS | Sony Group Corporation (JP) | 2021-09-16 | — | — | US | disclosed |
| US-10399964-B2 | Coumarin-linked taxanes for detection and circumvention of cellular efflux | THE UNIVERSITY OF KANSAS (US) | 2019-09-03 | — | — | US | disclosed |
| US-20170097333-A1 | CELL BASED ASSAY TO MEASURE THE T-CELL STIMULATING CAPACITY OF ANTI-LAG3 ANTIBODIES AND OTHER AGENTS | MERCK SHARP & DOHME CORP. (US) | 2017-04-06 | — | — | US | disclosed |
| US-20170097333-A1 | CELL BASED ASSAY TO MEASURE THE T-CELL STIMULATING CAPACITY OF ANTI-LAG3 ANTIBODIES AND OTHER AGENTS | MERCK SHARP & DOHME CORP. (US) | 2017-04-06 | — | — | US | disclosed |
| US-9139550-B2 | Fluorescence dye tagging scheme for mercury quantification and speciation | LOS GATOS RESEARCH (US) | 2015-09-22 | — | — | US | disclosed |
| US-20150125904-A1 | PROBE INCORPORATION MEDIATED BY ENZYMES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-05-07 | — | — | US | disclosed |
| US-20150125904-A1 | PROBE INCORPORATION MEDIATED BY ENZYMES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-05-07 | — | — | US | disclosed |
| WO-2014200872-A9 | PHARMACEUTICAL COMPOUNDS TARGETED BY MIF AFFINITY-TETHERED MOIETIES | RJS BIOLOGICS LLC (US) | 2015-02-05 | — | — | WO | disclosed |
| WO-2014200872-A1 | PHARMACEUTICAL COMPOUNDS TARGETED BY MIF AFFINITY-TETHERED MOIETIES | RJS BIOLOGICS LLC (US) | 2014-12-18 | — | — | WO | disclosed |
| WO-2013148189-A1 | PROBE INCORPORATION MEDIATED BY ENZYMES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-10-03 | — | — | WO | disclosed |
| US-20130040393-A1 | FLUORESCENCE DYE TAGGING SCHEME FOR MERCURY QUANTIFICATION AND SPECIATION | LOS GATOS RESEARCH (US) | 2013-02-14 | — | — | US | disclosed |
| US-20100029017-A1 | Mono-chlorinated hydroxycoumarin conjugates | BECTON, DICKINSON AND COMPANY | 2010-02-04 | — | — | US | disclosed |
| US-20100029017-A1 | Mono-chlorinated hydroxycoumarin conjugates | BECTON, DICKINSON AND COMPANY | 2010-02-04 | — | — | US | disclosed |
| US-20090156825-A1 | Fluorescent compounds that bind to histone deacetylase | MERCK SHARP & DOHME CORP. | 2009-06-18 | — | — | US | disclosed |
| US-20090156825-A1 | Fluorescent compounds that bind to histone deacetylase | MERCK SHARP & DOHME CORP. | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156825-A1 | Fluorescent compounds that bind to histone deacetylase | HDAC1, HDAC3, HDAC11 | GPR35 2920/4885MAOB 2637/4885MAOA 2749/4885 |
| US-10399964-B2 | Coumarin-linked taxanes for detection and circumvention of cellular efflux | SLC6A1, ABCB11, SLC6A11 | GPR35 1637/4885MAOB 1947/4885MAOA 2863/4885 |
| US-20100029017-A1 | Mono-chlorinated hydroxycoumarin conjugates | CLSPN, CLTC, HACD3 | GPR35 3783/4885MAOB 3474/4885MAOA 3032/4885 |
| US-20170097333-A1 | CELL BASED ASSAY TO MEASURE THE T-CELL STIMULATING CAPACITY OF ANTI-LAG3 ANTIBODIES AND OTHER AGENTS | ICOS, CD4, NFATC1 | GPR35 455/4885MAOB 4579/4885MAOA 4370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.