Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.70 |
| ▸ | ADRA1A | P35348 | 8/20 | 0.70 |
| ▸ | DRD3 | P35462 | 8/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.70 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.70 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.70 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.70 |
| ▸ | DRD1 | P21728 | 6/20 | 0.70 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.70 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.70 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.70 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.70 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.70 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.70 |
| ▸ | GFER | P55789 | 2/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.67 |
| ▸ | LMNA | P02545 | 7/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.65 |
| ▸ | DRD2 | P14416 | 5/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aceprometazine SCHEMBL142393 | 0.86 | HTR1A (0.79) | HTR1AADRA1ADRD3KCNH2CHRM2 | |
| Aceprometazine SCHEMBL29497450 | 0.86 | HTR1A (0.79) | HTR1AADRA1ADRD3KCNH2CHRM2 | |
| Aceprometazine SCHEMBL11491734 | 0.86 | HTR1A (0.79) | HTR1AADRA1ADRD3KCNH2CHRM2 | |
| Aceprometazine SCHEMBL29688253 | 0.86 | HTR1A (0.79) | HTR1AADRA1ADRD3KCNH2CHRM2 | |
| SCHEMBL11884942 | 0.85 | CYP2D6 (0.62) | HTR1AADRA1ADRD3KCNH2CHRM2 | |
| Methylpromazine SCHEMBL29354434 | 0.84 | CHRM2 (1.00) | HTR1AADRA1ADRD3KCNH2CHRM2 | |
| Methylpromazine SCHEMBL18994 | 0.84 | CHRM2 (1.00) | HTR1AADRA1ADRD3KCNH2CHRM2 | |
| Methylpromazine SCHEMBL18993 | 0.84 | CHRM2 (1.00) | HTR1AADRA1ADRD3KCNH2CHRM2 | |
| Methylpromazine SCHEMBL21293802 | 0.83 | GFER (0.82) | HTR1AADRA1ADRD3KCNH2CHRM2 | |
| Levomepromazine SCHEMBL27701483 | 0.83 | LMNA (0.88) | HTR1AADRA1ADRD3KCNH2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190314385-A1 | Process for Preparation of Chlorpromazine or its Pharmaceutically Acceptable Salts | SOLARA ACTIVE PHARMA SCIENCES LIMITED (IN) | 2019-10-17 | — | — | US | disclosed |
| EP-3533790-A2 | AN IMPROVED PROCESS FOR PREPARATION OF CHLORPROMAZINE OR ITS PHARMACEUTICALLY ACCEPTABLE SALTS | Solara Active Pharma Sciences Limited (IN) | 2019-09-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190314385-A1 | Process for Preparation of Chlorpromazine or its Pharmaceutically Acceptable Salts | CPNE4, CTSZ, CYP3A5 | HTR1A 492/4885ADRA1A 162/4885DRD3 1275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.