Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GLI1 | P08151 | 1/20 | 0.40 |
| ▸ | GLI2 | P10070 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.40 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.40 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.40 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTGIR | P43119 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21332569 | 0.92 | HIF1A (0.44) | HIF1ARAB9AMAPTSMN1; SMN2KMT2A | |
| SCHEMBL21332709 | 0.88 | RAB9A (0.46) | HIF1ARAB9ALMNACYP3A4HTT | |
| SCHEMBL21345753 | 0.84 | KMT2A (0.50) | HIF1ARAB9AMAPTSMN1; SMN2KMT2A | |
| SCHEMBL21332776 | 0.83 | PLAAT3 (0.55) | RAB9AMAPTGLI1GLI2SMN1; SMN2 | |
| SCHEMBL21332561 | 0.83 | KMT2A (0.53) | RAB9AMAPTHTTMMP13SMN1; SMN2 | |
| SCHEMBL21333665 | 0.82 | LTA4H (0.50) | HIF1ARAB9AMAPTGLI1GLI2 | |
| SCHEMBL21346280 | 0.81 | KMT2A (0.40) | HIF1APLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL21332630 | 0.79 | SLC5A1 (0.42) | MAPTLMNACYP3A4PLAAT3PLAAT5 | |
| SCHEMBL21332469 | 0.78 | SLC5A1 (0.61) | RAB9AMAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL21332514 | 0.78 | LTA4H (0.55) | RAB9AMAPTSMN1; SMN2EPHX2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11572337-B2 | Antibacterial agents: arylalkylcarboxamido phloroglucinols | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2023-02-07 | — | — | US | disclosed |
| US-11572337-B2 | Antibacterial agents: arylalkylcarboxamido phloroglucinols | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2023-02-07 | — | — | US | disclosed |
| US-20210017126-A1 | Antibacterial Agents: Arylalkylcarboxamido Phloroglucinols | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2021-01-21 | — | — | US | disclosed |
| US-20210017126-A1 | Antibacterial Agents: Arylalkylcarboxamido Phloroglucinols | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2021-01-21 | — | — | US | disclosed |
| WO-2019173507-A1 | ANTIBACTERIAL AGENTS : ARYLALKYLCARBOXAMIDO PHLOROGLUCINOLS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2019-09-12 | — | — | WO | disclosed |
| WO-2019173507-A1 | ANTIBACTERIAL AGENTS : ARYLALKYLCARBOXAMIDO PHLOROGLUCINOLS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2019-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11572337-B2 | Antibacterial agents: arylalkylcarboxamido phloroglucinols | RNGTT, FBL, POLR1C | EPHX1 4224/4885HIF1A 2639/4885AURKA 2816/4885 |
| US-20210017126-A1 | Antibacterial Agents: Arylalkylcarboxamido Phloroglucinols | RNGTT, FBL, POLR1C | EPHX1 4224/4885HIF1A 2639/4885AURKA 2816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.