Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 4/20 | 0.34 |
| ▸ | PPARA | Q07869 | 4/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | YWHAG | P61981 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7768833 | 0.78 | P2RY6 (0.51) | P2RY6HSD17B10CA1CA2TP53 | |
| Hydrochloric Acid SCHEMBL8743443 | 0.77 | TDP1 (0.56) | RAD52NPSR1HSD17B10TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL8978144 | 0.74 | P2RY6 (0.66) | P2RY6HSD17B10CA1CA2TP53 | |
| SCHEMBL8978084 | 0.72 | P2RY6 (0.68) | P2RY6HSD17B10CA1CA2TP53 | |
| SCHEMBL3763772 | 0.72 | P2RY6 (0.58) | P2RY6HSD17B10MAPT | |
| SCHEMBL7603799 | 0.69 | P2RY6 (0.63) | P2RY6HSD17B10CA1CA2TP53 | |
| SCHEMBL1853024 | 0.69 | P2RY6 (1.00) | P2RY6HSD17B10CA1CA2TP53 | |
| SCHEMBL9547715 | 0.69 | P2RY6 (1.00) | P2RY6HSD17B10CA1CA2TP53 | |
| SCHEMBL3765043 | 0.69 | CYP4Z1 (0.57) | P2RY6HSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL31276392 | 0.68 | P2RY6 (0.44) | P2RY6HSD17B10PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3762029-A1 | PAPER-BASED COLLECTION AND TEST DEVICES FOR BIOLOGICAL SAMPLES | Ohio State Innovation Foundation (US) | 2021-01-13 | — | — | EP | disclosed |
| US-20200400659-A1 | PAPER-BASED COLLECTION AND TEST DEVICES FOR BIOLOGICAL SAMPLES | OHIO STATE INNOVATION FOUNDATION | 2020-12-24 | — | — | US | disclosed |
| WO-2019173845-A1 | PAPER-BASED COLLECTION AND TEST DEVICES FOR BIOLOGICAL SAMPLES | OHIO STATE INNOVATION FOUNDATION (US) | 2019-09-12 | — | — | WO | disclosed |