Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 3/20 | 0.40 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157942 | 0.84 | L3MBTL1 (0.35) | APLNRMAPTL3MBTL1HPGDTDP1 | |
| SCHEMBL21362759 | 0.81 | LMNA (0.43) | APLNRMAPTL3MBTL1HPGDTDP1 | |
| SCHEMBL21352139 | 0.80 | MAPT (0.40) | APLNRMAPTL3MBTL1HPGDTDP1 | |
| SCHEMBL20157925 | 0.79 | ALDH1A1 (0.36) | APLNRMAPTALDH1A1LMNASLC6A2 | |
| SCHEMBL21362648 | 0.77 | ACHE (0.39) | TDP1ALDH1A1LMNATHRBSMN1; SMN2 | |
| SCHEMBL21550045 | 0.77 | DPP4 (0.35) | APLNRMAPTLMNANPSR1RAB9A | |
| SCHEMBL30910896 | 0.75 | F2RL1 (0.45) | F2RL1MAPTALDH1A1LMNATHRB | |
| SCHEMBL21831133 | 0.75 | F2RL1 (0.45) | F2RL1MAPTALDH1A1LMNATHRB | |
| SCHEMBL30133776 | 0.73 | F2RL1 (0.41) | F2RL1MAPTLMNASMN1; SMN2MAPK1 | |
| SCHEMBL21550255 | 0.73 | TRPA1 (0.33) | L3MBTL1LMNARAB9ASLC6A2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3539960-A1 | NITROGENOUS MACROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | Luoxin Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2019-09-18 | — | — | EP | disclosed |