Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157925 | 0.83 | ALDH1A1 (0.36) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL21362648 | 0.81 | ACHE (0.39) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL21352139 | 0.81 | MAPT (0.40) | LMNANPC1RAB9AMEN1KMT2A | |
| SCHEMBL21550045 | 0.81 | DPP4 (0.35) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL21362647 | 0.81 | F2RL1 (0.40) | LMNASLC6A2NPC1RAB9AL3MBTL1 | |
| SCHEMBL21550255 | 0.76 | TRPA1 (0.33) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL21550077 | 0.75 | TRPA1 (0.33) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL21564876 | 0.74 | LMNA (0.34) | LMNATRPA1CHRM1SLC6A2ADRA1A | |
| SCHEMBL21549993 | 0.73 | OPRM1 (0.38) | NPC1RAB9AMAPTHTTGAA | |
| SCHEMBL21550051 | 0.72 | ALDH1A1 (0.38) | LMNATRPA1CHRM1SLC6A2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3539960-A1 | NITROGENOUS MACROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | Luoxin Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2019-09-18 | — | — | EP | disclosed |