Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.46 |
| ▸ | DRD1 | P21728 | 2/20 | 0.42 |
| ▸ | DRD5 | P21918 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14046191 | 0.81 | HRH3 (0.48) | HRH3DRD1ACACBDRD2DRD3 | |
| SCHEMBL14102479 | 0.81 | HRH3 (0.48) | HRH3DRD1ACACBDRD2DRD3 | |
| SCHEMBL20884710 | 0.78 | HRH3 (0.37) | HRH3DRD1DRD5MAOAMAOB | |
| SCHEMBL12628112 | 0.76 | MAOA (0.55) | DRD1DRD5MAOAMAOBSLC6A4 | |
| SCHEMBL25814865 | 0.74 | DRD2 (0.51) | HRH3DRD1DRD5ACACBDRD2 | |
| SCHEMBL29310399 | 0.74 | NMT1 (0.34) | DRD1DRD5DRD2DRD3PNMT | |
| SCHEMBL1619374 | 0.74 | MAOA (0.52) | DRD1DRD5MAOAMAOBSLC6A4 | |
| SCHEMBL24253320 | 0.74 | HRH3 (0.38) | HRH3DRD1DRD5MAOAMAOB | |
| SCHEMBL22544135 | 0.74 | DRD2 (0.43) | HRH3ACACBDRD2DRD3 | |
| SCHEMBL24671706 | 0.73 | MAOA (0.52) | DRD1DRD5MAOAMAOBSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190282703-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE (ENPP) CONJUGATES AND USES THEREOF | ABBVIE INC. | 2019-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190282703-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE (ENPP) CONJUGATES AND USES THEREOF | ENPP1, ENPP3, ENPEP | HRH3 4533/4885DRD1 4411/4885DRD5 3848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.