SCHEMBL2189195

SCHEMBL2189195

Cc1ccccc1-c1ccnc(-c2ccccc2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 4/20 0.52
ASIC3 Q9UHC3 1/20 0.50
ENPP3 O14638 1/20 0.46
ENPP1 P22413 1/20 0.46
GRM5 P41594 1/20 0.46
ALDH1A1 P00352 2/20 0.45
KDM4E B2RXH2 1/20 0.45
CTDSP1 Q9GZU7 1/20 0.45
PIM1 P11309 1/20 0.44
CDK1 P06493 1/20 0.43
MAPKAPK2 P49137 1/20 0.43
MAPKAPK3 Q16644 1/20 0.43
MAPKAPK5 Q8IW41 1/20 0.43
MKNK1 Q9BUB5 1/20 0.43
LDHA P00338 1/20 0.42
HTR7 P34969 1/20 0.42
NPC1 O15118 1/20 0.42
HPGD P15428 1/20 0.42
TSHR P16473 1/20 0.42
RAB9A P51151 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15743711 0.86 TGFBR1 (0.56) TGFBR1ASIC3GRM5ALDH1A1NPC1
SCHEMBL14979471 0.85 TGFBR1 (0.49) TGFBR1ASIC3ALDH1A1KDM4ECTDSP1
SCHEMBL21363952 0.83 TGFBR1 (0.50) TGFBR1GRM5ALDH1A1NPC1TSHR
SCHEMBL18025826 0.82 TGFBR1 (0.45) TGFBR1ASIC3ALDH1A1KDM4ECTDSP1
SCHEMBL24104234 0.82 BRD4 (0.50) TGFBR1GRM5HTR7LCKKDR
SCHEMBL21167060 0.81 TGFBR1 (0.52) TGFBR1ASIC3GRM5ALDH1A1KDM4E
SCHEMBL21692157 0.80 ASIC3 (0.65) TGFBR1ASIC3ALDH1A1KDM4ECTDSP1
SCHEMBL22426647 0.79 PDK2 (0.47) TGFBR1ALDH1A1HTR7TSHRLCK
SCHEMBL28196231 0.79 ENPP3 (0.54) ENPP3ENPP1ALDH1A1KDM4ENPC1
SCHEMBL15506216 0.79 ASIC3 (0.50) TGFBR1ASIC3ALDH1A1KDM4ECTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12127470-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-10-22 US disclosed
EP-4223854-A2 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2023-08-09 EP disclosed
EP-4223854-A2 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2023-08-09 EP disclosed
EP-3399005-B1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2023-05-31 EP disclosed
US-20230053347-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-02-23 US disclosed
US-20230053347-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-02-23 US disclosed
US-11482685-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-10-25 US disclosed
US-20210074931-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-03-11 US disclosed
US-20210074931-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-03-11 US disclosed
US-10892426-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-01-12 US disclosed
US-8519384-B2 Phosphorescent materials UNIVERSAL DISPLAY CORPORATION (US) 2013-08-27 US disclosed
CN-102232105-A phosphorescent material UNIVERSAL DISPLAY CORP 2011-11-02 CN disclosed
US-20110227049-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2011-09-22 US disclosed
US-20110227049-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2011-09-22 US disclosed
US-20110227049-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2011-09-22 US disclosed
EP-2342305-A1 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2011-07-13 EP disclosed
WO-2010028151-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2010-03-11 WO disclosed
WO-2010028151-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2010-03-11 WO disclosed
WO-2010027583-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2010-03-11 WO disclosed
WO-2010027583-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2010-03-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12127470-B2 Organic electroluminescent materials and devices SOD1, CLTB, L1CAM TGFBR1 2490/4885ASIC3 1471/4885ENPP3 2621/4885
US-10892426-B2 Organic electroluminescent materials and devices OCIAD2, LMNB2, RUVBL2 TGFBR1 4011/4885ASIC3 2338/4885ENPP3 2023/4885
US-20210074931-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES EML4, MCM4, KCNMB4 TGFBR1 2143/4885ASIC3 2639/4885ENPP3 3273/4885
US-20110227049-A1 PHOSPHORESCENT MATERIALS PPIP5K2, PAICS, IP6K1 TGFBR1 2674/4885ASIC3 761/4885ENPP3 261/4885
US-11482685-B2 Organic electroluminescent materials and devices EML4, MCM4, KCNMB4 TGFBR1 2143/4885ASIC3 2639/4885ENPP3 3273/4885
US-20230053347-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, CLTB, L1CAM TGFBR1 2490/4885ASIC3 1471/4885ENPP3 2621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.