Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.31 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.30 |
| ▸ | CBFB | Q13951 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21363956 | 0.89 | GRM5 (0.40) | GRM5ALDH1A1TGFBR1BRD4MAPK10 | |
| SCHEMBL21364027 | 0.82 | GRM5 (0.43) | GRM5ALDH1A1TGFBR1BRD4MAPK10 | |
| SCHEMBL21364094 | 0.77 | TGFBR1 (0.40) | GRM5ALDH1A1TGFBR1BRD4 | |
| SCHEMBL21364026 | 0.75 | TGFBR1 (0.53) | ALDH1A1TGFBR1BRD4MAPK10 | |
| SCHEMBL21363961 | 0.73 | GABRA1 (0.38) | GABRA1GABRB2ALDH1A1NR1H3NR1H2 | |
| SCHEMBL21363952 | 0.72 | TGFBR1 (0.50) | GRM5ALDH1A1TGFBR1BRD4MAPK10 | |
| SCHEMBL21364095 | 0.72 | BRD4 (0.42) | GRM5ALDH1A1TGFBR1BRD4 | |
| SCHEMBL28353322 | 0.71 | CCR1 (0.55) | GABRA1GABRB2ALDH1A1 | |
| SCHEMBL17173320 | 0.70 | BRD4 (0.41) | GRM5TGFBR1BRD4MAPK10 | |
| SCHEMBL21363963 | 0.70 | KDM4C (0.35) | GABRA1GABRB2TGFBR1NR1H3NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11145821-B2 | Organic electroluminescence device and polycyclic compound for organic electroluminescence device | SAMSUNG DISPLAY CO., LTD. (KR) | 2021-10-12 | — | — | US | disclosed |
| US-20190288216-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2019-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11145821-B2 | Organic electroluminescence device and polycyclic compound for organic electroluminescence device | LEF1, SLC25A21, EMC2 | GABRA1 4553/4885GABRB2 4403/4885GRM5 4602/4885 |
| US-20190288216-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE | LEF1, SLC25A21, EMC2 | GABRA1 4553/4885GABRB2 4403/4885GRM5 4602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.