Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 8/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 8/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 8/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 8/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.31 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21363960 | 0.89 | KDM4C (0.38) | KDM4CALOX5APFEN1PHF8GRM5 | |
| SCHEMBL21363956 | 0.70 | GRM5 (0.40) | GRM5 | |
| SCHEMBL9613219 | 0.69 | PRKDC (0.39) | CYP3A4CYP2C9CDK1 | |
| SCHEMBL21364027 | 0.68 | GRM5 (0.43) | GRM5 | |
| SCHEMBL21363963 | 0.67 | KDM4C (0.35) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL12345156 | 0.66 | ASIC3 (0.55) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL9973738 | 0.66 | CYP2A6 (0.58) | CYP3A4CYP2C9 | |
| SCHEMBL21363955 | 0.66 | NOS3 (0.37) | ALOX5APFEN1CYP2C9 | |
| SCHEMBL18272725 | 0.64 | ASIC3 (0.43) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL21364026 | 0.64 | TGFBR1 (0.53) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11145821-B2 | Organic electroluminescence device and polycyclic compound for organic electroluminescence device | SAMSUNG DISPLAY CO., LTD. (KR) | 2021-10-12 | — | — | US | disclosed |
| US-20190288216-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2019-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11145821-B2 | Organic electroluminescence device and polycyclic compound for organic electroluminescence device | LEF1, SLC25A21, EMC2 | GABRG2 4660/4885GABRB3 4583/4885GABRA5 4785/4885 |
| US-20190288216-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE | LEF1, SLC25A21, EMC2 | GABRG2 4660/4885GABRB3 4583/4885GABRA5 4785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.