Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.51 |
| ▸ | RARG | P13631 | 2/20 | 0.51 |
| ▸ | RARA | P10276 | 1/20 | 0.51 |
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16670830 | 0.90 | RARB (0.56) | RARBRARGRARARXRATRPA1 | |
| SCHEMBL18084341 | 0.84 | RARB (0.54) | RARBRARGRARARXRATRPA1 | |
| SCHEMBL10044151 | 0.84 | RARB (0.54) | RARBRARGRARARXRATRPA1 | |
| SCHEMBL16671579 | 0.83 | RARB (0.49) | RARBRARGRARARXRATRPA1 | |
| SCHEMBL24475285 | 0.81 | RARB (0.58) | RARBRARGRARARXRATRPA1 | |
| SCHEMBL18084306 | 0.81 | RARB (0.51) | RARBRARGRARARXRATRPA1 | |
| SCHEMBL703377 | 0.80 | RARB (0.60) | RARBRARGRARARXRATRPA1 | |
| SCHEMBL9202781 | 0.80 | RARB (0.60) | RARBRARGRARARXRATRPA1 | |
| SCHEMBL703376 | 0.80 | RARB (0.60) | RARBRARGRARARXRATRPA1 | |
| SCHEMBL24228266 | 0.78 | ALOX15 (0.57) | RARBRARGRARARXRATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858948-B2 | Hydrogenation of carbonyls with tetradentate PNNP ligand ruthenium complexes | FIRMENICH SA (CH) | 2024-01-02 | — | — | US | disclosed |
| US-11858948-B2 | Hydrogenation of carbonyls with tetradentate PNNP ligand ruthenium complexes | FIRMENICH SA (CH) | 2024-01-02 | — | — | US | disclosed |
| US-11858948-B2 | Hydrogenation of carbonyls with tetradentate PNNP ligand ruthenium complexes | FIRMENICH SA (CH) | 2024-01-02 | — | — | US | disclosed |
| EP-3700914-B1 | HYDROGENATION OF CARBONYLS WITH TETRADENTATE PNNP LIGAND RUTHENIUM COMPLEXES | FIRMENICH & CIE (CH) | 2022-02-02 | — | — | EP | disclosed |
| EP-3700914-B1 | HYDROGENATION OF CARBONYLS WITH TETRADENTATE PNNP LIGAND RUTHENIUM COMPLEXES | FIRMENICH & CIE (CH) | 2022-02-02 | — | — | EP | disclosed |
| US-20200399299-A1 | HYDROGENATION OF CARBONYLS WITH TETRADENTATE PNNP LIGAND RUTHENIUM COMPLEXES | FIRMENICH SA (CH) | 2020-12-24 | — | — | US | disclosed |
| WO-2019175158-A1 | HYDROGENATION OF CARBONYLS WITH TETRADENTATE PNNP LIGAND RUTHENIUM COMPLEXES | FIRMENICH SA (CH) | 2019-09-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11858948-B2 | Hydrogenation of carbonyls with tetradentate PNNP ligand ruthenium complexes | ADH1C, ADH1A, ADH5 | RARB 2983/4885RARG 2648/4885RARA 3378/4885 |
| US-20200399299-A1 | HYDROGENATION OF CARBONYLS WITH TETRADENTATE PNNP LIGAND RUTHENIUM COMPLEXES | ADH1C, ADH1A, ADH5 | RARB 2983/4885RARG 2648/4885RARA 3378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.