SCHEMBL21373902

SCHEMBL21373902

C=C(C)C(=O)Oc1ccc(COCC2CO2)cc1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
KMT2A Q03164 3/20 0.43
ATM Q13315 1/20 0.43
ELANE P08246 1/20 0.43
MGLL Q99685 3/20 0.36
TP53 P04637 2/20 0.35
MAPT P10636 2/20 0.35
HPGD P15428 2/20 0.35
TSHR P16473 2/20 0.35
LMNA P02545 2/20 0.35
PKM P14618 2/20 0.35
MEN1 O00255 1/20 0.35
CYP1A2 P05177 1/20 0.35
PPARG P37231 1/20 0.35
HIF1A Q16665 1/20 0.35
GAA P10253 1/20 0.35
PTPN1 P18031 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16241157 0.84 ALDH1A1 (0.53) ALDH1A1KMT2AATMELANEMGLL
SCHEMBL24709164 0.83 ALDH1A1 (0.55) ALDH1A1KMT2AATMELANETP53
SCHEMBL21373884 0.81 THRB (0.49) ALDH1A1MGLLLMNAPKMGAA
SCHEMBL7923720 0.81 KMT2A (0.50) ALDH1A1KMT2AATMELANETP53
SCHEMBL7603742 0.80 ALDH1A1 (0.51) ALDH1A1KMT2AATMELANETP53
SCHEMBL4403982 0.80 ALDH1A1 (0.51) ALDH1A1KMT2AATMELANEMGLL
SCHEMBL29016254 0.79 ALDH1A1 (0.58) ALDH1A1MGLLTP53TSHR
SCHEMBL29259133 0.79 ALDH1A1 (0.51) ALDH1A1KMT2AATMELANEMGLL
SCHEMBL21680120 0.79 ALDH1A1 (0.57) ALDH1A1KMT2AMGLLTP53MAPT
Methacrylic Acid SCHEMBL3864596 0.78 KMT2A (0.47) ALDH1A1KMT2AATMELANETP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11667669-B2 Epoxy-(meth)acrylate monomers and polymers and methods of making and using the same ROWAN UNIVERSITY (US) 2023-06-06 US disclosed
US-11667669-B2 Epoxy-(meth)acrylate monomers and polymers and methods of making and using the same ROWAN UNIVERSITY (US) 2023-06-06 US disclosed
US-11118047-B2 Composition for a glass fiber-reinforced polyolefin resin material, glass fiber-reinforced polyolefin resin material and its production method, and composite FURUKAWA ELECTRIC CO., LTD. (JP) 2021-09-14 US disclosed
US-20200048301-A1 EPOXY-(METH)ACRYLATE MONOMERS AND POLYMERS AND METHODS OF MAKING AND USING THE SAME ROWAN UNIVERSITY 2020-02-13 US disclosed
US-20190292360-A1 COMPOSITION FOR A GLASS FIBER-REINFORCED POLYOLEFIN RESIN MATERIAL, GLASS FIBER-REINFORCED POLYOLEFIN RESIN MATERIAL AND ITS PRODUCTION METHOD, AND COMPOSITE FURUKAWA ELECTRIC CO., LTD. (JP) 2019-09-26 US disclosed
EP-3543290-A1 COMPOSITION FOR GLASS FIBER-REINFORCED POLYOLEFIN RESIN MATERIALS, GLASS FIBER-REINFORCED POLYOLEFIN RESIN MATERIAL, METHOD FOR PRODUCING SAME, AND COMPOSITE BODY Furukawa Electric Co., Ltd. (JP) 2019-09-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11667669-B2 Epoxy-(meth)acrylate monomers and polymers and methods of making and using the same PTGES, PTGIS, EPX ALDH1A1 102/4885KMT2A 1609/4885ATM 2362/4885
US-20200048301-A1 EPOXY-(METH)ACRYLATE MONOMERS AND POLYMERS AND METHODS OF MAKING AND USING THE SAME PTGES, PTGIS, EPX ALDH1A1 102/4885KMT2A 1609/4885ATM 2362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.