Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | PHGDH | O43175 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20385009 | 0.78 | TRPM8 (0.44) | NPSR1TRPM8ALDH1A1KMT2ATSHR | |
| SCHEMBL23435086 | 0.76 | ALDH1A1 (0.34) | NPSR1TRPM8ALDH1A1KMT2ATSHR | |
| SCHEMBL19135766 | 0.74 | NPSR1 (0.38) | NPSR1TRPM8ALDH1A1KMT2ANPC1 | |
| SCHEMBL18753397 | 0.74 | NPSR1 (0.38) | NPSR1TRPM8ALDH1A1KMT2ANPC1 | |
| SCHEMBL22002870 | 0.74 | NPSR1 (0.38) | NPSR1TRPM8ALDH1A1KMT2ATSHR | |
| SCHEMBL25638939 | 0.70 | FAAH (0.41) | ALDH1A1KMT2ATSHRNPC1POLB | |
| SCHEMBL24895937 | 0.70 | ALDH1A1 (0.31) | ALDH1A1TSHRGLA | |
| SCHEMBL18828278 | 0.70 | — | — | |
| SCHEMBL17636176 | 0.69 | INSR (0.33) | NPSR1ALDH1A1KMT2AHTTMEN1 | |
| SCHEMBL21913825 | 0.69 | FAAH (0.39) | ALDH1A1KMT2ATSHRNPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019177043-A1 | ANILINE DERIVATIVE AND USE THEREOF | 日産化学株式会社 | 2019-09-19 | — | — | WO | disclosed |