Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ACLY | P53396 | 2/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | WDR5 | P61964 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13337363 | 0.85 | ALDH1A1 (0.49) | METAP2ALDH1A1KDM4EMRGPRX1TSPO | |
| SCHEMBL21381491 | 0.84 | ACLY (0.61) | METAP2ACLYKDM4EMRGPRX1 | |
| SCHEMBL219601 | 0.81 | ALDH1A1 (0.71) | METAP2ALDH1A1KDM1AAPEX1MEN1 | |
| SCHEMBL31393942 | 0.78 | ACLY (0.62) | ALDH1A1ACLYMEN1KMT2AKDM4E | |
| SCHEMBL21384569 | 0.77 | ACLY (0.48) | ACLYKDM4ETDP1MRGPRX1TSPO | |
| SCHEMBL23141230 | 0.75 | METAP2 (0.60) | METAP2ALDH1A1KDM1AAPEX1MEN1 | |
| SCHEMBL31046908 | 0.75 | METAP2 (0.60) | METAP2ALDH1A1KDM1AAPEX1MEN1 | |
| SCHEMBL3377038 | 0.74 | ACLY (0.60) | ACLYCYP3A4CYP2C9CYP2C19MRGPRX1 | |
| SCHEMBL13337359 | 0.73 | KIF11 (0.36) | ALDH1A1ACLYTDP1WDR5MRGPRX1 | |
| SCHEMBL21394417 | 0.73 | MRGPRX1 (0.53) | KDM1AMRGPRX1TSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019179436-A1 | ACID AMIDE COMPOUND AND USE THEREOF IN TREATMENT OF CANCERS | 成都海创药业有限公司 | 2019-09-26 | — | — | WO | disclosed |