Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390870 | 0.89 | JAK1 (0.30) | JAK1 | |
| SCHEMBL21391098 | 0.87 | JAK1 (0.31) | CNR2JAK1 | |
| SCHEMBL21390924 | 0.76 | HTR3A (0.34) | JAK1 | |
| SCHEMBL21390810 | 0.76 | CYP19A1 (0.32) | JAK1RORCHDAC1 | |
| SCHEMBL21391086 | 0.75 | AR (0.33) | JAK1HDAC1 | |
| SCHEMBL21390979 | 0.75 | HDAC1 (0.32) | JAK1HDAC1 | |
| SCHEMBL21390787 | 0.75 | RORC (0.30) | RORCHDAC1 | |
| SCHEMBL21391159 | 0.75 | SMN1; SMN2 (0.35) | HDAC1 | |
| SCHEMBL23132031 | 0.74 | CYP11B2 (0.41) | HDAC1 | |
| SCHEMBL21390892 | 0.73 | KDM4E (0.33) | JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |