Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 4/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | CCR9 | P51686 | 1/20 | 0.31 |
| ▸ | ALB | P02768 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | APLNR | P35414 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390801 | 0.92 | PTGDR2 (0.36) | ACSS2PTGDR2TRPV4TLR8TLR7 | |
| SCHEMBL21390806 | 0.92 | PTGDR2 (0.35) | ACSS2PTGDR2TRPV4 | |
| SCHEMBL21390957 | 0.87 | NTRK1 (0.33) | ACSS2APEX1 | |
| SCHEMBL21390799 | 0.87 | PTGDR2 (0.31) | PTGDR2 | |
| SCHEMBL21390797 | 0.87 | PTGDR2 (0.31) | PTGDR2 | |
| SCHEMBL21390670 | 0.86 | TRPV4 (0.35) | ACSS2PTGDR2TRPV4TLR8TLR7 | |
| SCHEMBL21390678 | 0.85 | TRPV4 (0.32) | ACSS2PTGDR2TRPV4TLR8TLR7 | |
| SCHEMBL21390820 | 0.85 | ACSS2 (0.33) | ACSS2APEX1 | |
| SCHEMBL21390813 | 0.83 | IDH1 (0.33) | ACSS2PTGDR2TRPV4TLR8TLR7 | |
| SCHEMBL21391179 | 0.82 | ACSS2 (0.33) | ACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |