Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.31 |
| ▸ | ACLY | P53396 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391061 | 0.90 | ACSS2 (0.33) | ACSS2HDAC1BRD4CREBBP | |
| SCHEMBL21391163 | 0.82 | CYP19A1 (0.32) | ACSS2HDAC1BRD4CREBBP | |
| SCHEMBL21390668 | 0.81 | HDAC1 (0.35) | ACSS2HDAC1 | |
| SCHEMBL21391063 | 0.81 | HDAC1 (0.36) | ACSS2HDAC1 | |
| SCHEMBL21391060 | 0.81 | HDAC1 (0.36) | ACSS2HDAC1 | |
| SCHEMBL18791989 | 0.80 | TRPV4 (0.39) | ACSS2TRPV4ACACB | |
| SCHEMBL18791990 | 0.80 | TRPV4 (0.39) | ACSS2TRPV4ACACB | |
| SCHEMBL20110988 | 0.80 | TRPV4 (0.39) | ACSS2TRPV4ACACB | |
| SCHEMBL21390781 | 0.80 | BRD4 (0.33) | BRD4CREBBP | |
| SCHEMBL21391036 | 0.79 | HDAC1 (0.35) | ACSS2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |