Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21392086 | 0.73 | — | — | |
| SCHEMBL21392345 | 0.68 | CTPS1 (0.37) | CTPS1 | |
| SCHEMBL21392067 | 0.64 | — | — | |
| SCHEMBL21391990 | 0.63 | GAA (0.33) | CTPS1 | |
| SCHEMBL21392034 | 0.58 | ABL1 (0.31) | — | |
| SCHEMBL14642749 | 0.58 | ADORA2B (0.45) | — | |
| SCHEMBL22762464 | 0.56 | ATAD2 (0.41) | — | |
| SCHEMBL21387600 | 0.55 | CTPS1 (0.31) | CTPS1 | |
| SCHEMBL21392042 | 0.55 | HPGD (0.33) | — | |
| SCHEMBL24725095 | 0.55 | KDM4E (0.37) | CTPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019179652-A1 | AMINOPYRIMIDINE DERIVATIVES AS CTPS1 INHIBITORS | STEP PHARMA S.A.S. (FR) | 2019-09-26 | — | — | WO | disclosed |
| WO-2019180244-A1 | AMINOPYRIMIDINE DERIVATIVES AS CTPS1 INHIBITORS | STEP PHARMA S.A.S. (FR) | 2019-09-26 | — | — | WO | disclosed |