Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | YTHDF3 | Q7Z739 | 1/20 | 0.39 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.39 |
| ▸ | YTHDF1 | Q9BYJ9 | 1/20 | 0.39 |
| ▸ | YTHDF2 | Q9Y5A9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21384138 | 0.80 | NR3C2 (0.53) | LMNANR3C2MAPT | |
| SCHEMBL21394569 | 0.76 | NOS3 (0.50) | TAAR1PNMTMPOBACE1HTR3E | |
| SCHEMBL3300276 | 0.75 | PNMT (0.65) | TAAR1PNMTHTR3EHTR3BHTR3A | |
| SCHEMBL1501368 | 0.74 | ALDH1A1 (0.55) | TAAR1PNMTHTR3EHTR3BHTR3A | |
| Hydrochloric Acid SCHEMBL21384143 | 0.74 | NOS1 (0.49) | TAAR1PNMTMPOBACE1 | |
| SCHEMBL29358615 | 0.73 | CCR2 (0.50) | IGF1RLMNANR3C2 | |
| SCHEMBL21394568 | 0.73 | CCR2 (0.50) | IGF1RLMNANR3C2 | |
| SCHEMBL10933007 | 0.70 | PNMT (0.46) | TAAR1PNMTBACE1HTR3EHTR3B | |
| SCHEMBL3301781 | 0.69 | PNMT (0.58) | TAAR1PNMTHTR3EHTR3BHTR3A | |
| SCHEMBL18586524 | 0.68 | MPO (0.55) | TAAR1PNMTMPOHTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |