Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.32 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394895 | 0.89 | LMNA (0.37) | LMNASAE1UBA2USP2THRB | |
| SCHEMBL21395004 | 0.86 | ALDH1A1 (0.45) | LMNASAE1UBA2ALDH1A1SMN1; SMN2 | |
| SCHEMBL21395273 | 0.74 | LMNA (0.47) | LMNASAE1UBA2USP2THRB | |
| SCHEMBL22479641 | 0.74 | LMNA (0.50) | LMNASAE1UBA2USP2THRB | |
| SCHEMBL21384024 | 0.71 | MARS1 (0.43) | LMNASAE1UBA2USP2THRB | |
| SCHEMBL21383951 | 0.69 | PTGER4 (0.43) | LMNASAE1UBA2USP2THRB | |
| SCHEMBL21395278 | 0.65 | RAB9A (0.41) | ALDH1A1RAB9A | |
| SCHEMBL29353756 | 0.62 | SMN1; SMN2 (0.41) | LMNASAE1UBA2ALDH1A1SMN1; SMN2 | |
| SCHEMBL29358443 | 0.62 | RAB9A (0.46) | LMNASAE1UBA2ALDH1A1SMN1; SMN2 | |
| SCHEMBL21383972 | 0.62 | PTGS2 (0.44) | LMNASAE1UBA2USP2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |