Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 6/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 4/20 | 0.43 |
| ▸ | CACNA1I | Q9P0X4 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21395084 | 0.89 | AHR (0.39) | CACNA1HNPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL21394649 | 0.84 | P2RX3 (0.45) | CACNA1HCACNA1GCACNA1INPC1RAB9A | |
| SCHEMBL29357599 | 0.84 | NPC1 (0.47) | CACNA1HCACNA1GCACNA1INPC1RAB9A | |
| SCHEMBL21394824 | 0.84 | NPC1 (0.47) | CACNA1HCACNA1GCACNA1INPC1RAB9A | |
| SCHEMBL21395147 | 0.82 | NPC1 (0.39) | CACNA1HCACNA1GCACNA1INPC1RAB9A | |
| SCHEMBL21394575 | 0.80 | RAB9A (0.65) | CACNA1HCACNA1GCACNA1INPC1RAB9A | |
| SCHEMBL29442886 | 0.80 | RAB9A (0.65) | CACNA1HCACNA1GCACNA1INPC1RAB9A | |
| SCHEMBL21394578 | 0.80 | L3MBTL1 (0.46) | CACNA1HNPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL29355468 | 0.80 | L3MBTL1 (0.46) | CACNA1HNPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL21395082 | 0.80 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2GRM5CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |