Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1086964 | 0.79 | THRB (0.48) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL5831740 | 0.79 | THRB (0.48) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL18843939 | 0.79 | ALDH1A1 (0.43) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL24755314 | 0.76 | TSHR (0.46) | THRBTSHRALDH1A1 | |
| SCHEMBL18636940 | 0.76 | HCAR2 (0.41) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL15525410 | 0.75 | HCAR2 (0.39) | THRBTSHRALDH1A1HTTHCAR2 | |
| Fumaric Acid SCHEMBL690033 | 0.75 | THRB (0.48) | THRBTSHRALDH1A1POLBAPEX1 | |
| Fumaric Acid SCHEMBL28356830 | 0.75 | THRB (0.48) | THRBTSHRALDH1A1POLBAPEX1 | |
| Maleic Acid SCHEMBL690032 | 0.75 | THRB (0.48) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL15453344 | 0.74 | HCAR2 (0.41) | TSHRALDH1A1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9765159-B2 | Redispersible nanoparticles | MERCK PATENT GMBH (DE) | 2017-09-19 | — | — | US | disclosed |
| US-8586659-B2 | Redispersible surfaced-modified particles | MERCK PATENT GMBH (DE) | 2013-11-19 | — | — | US | disclosed |
| US-8188180-B2 | Binding agent | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-05-29 | — | — | US | disclosed |
| US-20110054074-A1 | ADHESIVE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG | 2011-03-03 | — | — | US | disclosed |
| US-20100215959-A1 | SILANES | MERCK PATENT GMBH (DE) | 2010-08-26 | — | — | US | disclosed |
| US-20100120935-A1 | BINDING AGENT | MERCK PATENT GESELLSCHAFT (DE) | 2010-05-13 | — | — | US | disclosed |
| US-20100092761-A1 | NANOPARTICLES | MERCK PATENT GESELLSCHAFT (DE) | 2010-04-15 | — | — | US | disclosed |
| US-20100010137-A1 | REDISPERSIBLE SURFACED-MODIFIED PARTICLES | MERCK PATENT GESELLSCHAFT (DE) | 2010-01-14 | — | — | US | disclosed |
| US-20090203838-A1 | REDISPERSIBLE NANOPARTICLES | MERCK PATENT GESELLSCHAFT (DE) | 2009-08-13 | — | — | US | disclosed |
| US-7488769-B2 | Aqueous dispersion of inorganic nanoparticles, method for the production and use thereof | BASF COATINGS AG (DE) | 2009-02-10 | — | — | US | disclosed |
| US-20080248289-A1 | Zinc Oxide Nanoparticles | MERCK PATENT GESELLSCHAFT (DE) | 2008-10-09 | — | — | US | disclosed |
| US-20050159523-A1 | Aqueous dispersion of inorganic nanoparticles, method for the production and use thereof | BASF CORPORATION, 26701 TELEGRAPH ROAD (US) | 2005-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100215959-A1 | SILANES | SGMS1, SGMS2, SUMO3 | THRB 4662/4885TSHR 3867/4885ALDH1A1 2286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.