SCHEMBL21399367

SCHEMBL21399367

Cc1c(Cl)nc(-c2ccccc2)nc1-c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.59
KMT2A Q03164 4/20 0.55
MEN1 O00255 3/20 0.55
HTT P42858 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.50
ALDH1A1 P00352 4/20 0.49
HPGD P15428 3/20 0.49
KDM4E B2RXH2 3/20 0.46
PKM P14618 2/20 0.46
POLB P06746 2/20 0.46
MAPT P10636 1/20 0.46
RAB9A P51151 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
DPP4 P27487 3/20 0.44
ADK P55263 2/20 0.44
GLA P06280 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ADORA3 P0DMS8 1/20 0.42
ADORA2A P29274 1/20 0.42
ADORA1 P30542 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25073556 0.96 LMNA (0.56) LMNAKMT2AMEN1HTTL3MBTL1
SCHEMBL1373850 0.88 LMNA (0.68) LMNAKMT2AMEN1HTTL3MBTL1
SCHEMBL10205915 0.86 L3MBTL1 (0.60) LMNAKMT2AMEN1L3MBTL1ALDH1A1
SCHEMBL603548 0.84 KDM4E (0.48) LMNAKMT2AMEN1HTTL3MBTL1
SCHEMBL7503985 0.82 LMNA (0.72) LMNAKMT2AMEN1HTTL3MBTL1
SCHEMBL25098396 0.81 LMNA (0.41) LMNAKMT2AMEN1HTTL3MBTL1
SCHEMBL12377799 0.80 L3MBTL1 (0.54) LMNAKMT2AMEN1HTTL3MBTL1
SCHEMBL11145225 0.79 XDH (0.51) LMNAALDH1A1HPGDKDM4EPOLB
SCHEMBL13114121 0.79 ALDH1A1 (0.55) KMT2AMEN1L3MBTL1ALDH1A1HPGD
SCHEMBL24169563 0.79 AHR (0.44) LMNAKMT2AMEN1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11737358-B2 Compound and organic light emitting device comprising same LG CHEM, LTD. (KR) 2023-08-22 US disclosed
US-11737358-B2 Compound and organic light emitting device comprising same LG CHEM, LTD. (KR) 2023-08-22 US disclosed
EP-4227301-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LT Materials Co., Ltd. (KR) 2023-08-16 EP disclosed
EP-4206198-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT-EMITTING DEVICE LT Materials Co., Ltd. (KR) 2023-07-05 EP disclosed
WO-2022262300-A1 NEUTRAL IRIDIUM COMPLEX CONTAINING BIPHENYL DERIVATIVE LIGAND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 江苏科技大学 2022-12-22 WO disclosed
US-20200303655-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2020-09-24 US disclosed
WO-2019182402-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2019-09-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11737358-B2 Compound and organic light emitting device comprising same ARNT, CYP1A1, AHR LMNA 1963/4885KMT2A 1033/4885MEN1 1470/4885
US-20200303655-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME ARNT, CYP1A1, AHR LMNA 1963/4885KMT2A 1033/4885MEN1 1470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.