Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ACHE | P22303 | 13/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21404684 | 0.95 | ACHE (0.50) | TSHRACHETHRB | |
| SCHEMBL21404678 | 0.95 | ACHE (0.50) | TSHRACHETHRB | |
| SCHEMBL10752198 | 0.95 | TSHR (0.45) | TSHRACHETHRB | |
| SCHEMBL21404622 | 0.94 | THRB (0.48) | TSHRACHETHRBPOLBAPEX1 | |
| SCHEMBL21404645 | 0.94 | THRB (0.48) | TSHRACHETHRBPOLBAPEX1 | |
| SCHEMBL21404651 | 0.94 | THRB (0.48) | TSHRACHETHRBPOLBAPEX1 | |
| SCHEMBL21404633 | 0.94 | THRB (0.48) | TSHRACHETHRBPOLBAPEX1 | |
| SCHEMBL21404721 | 0.94 | THRB (0.48) | TSHRACHETHRBPOLBAPEX1 | |
| SCHEMBL5925097 | 0.90 | ACHE (0.45) | TSHRACHETHRB | |
| SCHEMBL16223361 | 0.89 | TSHR (0.62) | TSHRACHETHRBPOLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4717249-A1 | DENTAL COMPOSITION | Shofu Inc. (JP) | 2026-04-01 | — | — | EP | disclosed |
| US-20260083642-A1 | DENTAL COMPOSITION | SHOFU INC (JP) | 2026-03-26 | — | — | US | disclosed |
| CN-112771057-B | Free radical polymerizable silane coupling compound with urethane bond based on diisocyanate | 株式会社松风 | 2024-12-20 | — | — | CN | disclosed |
| US-12152045-B2 | Silane coupling compounds and medical and/or dental curable compositions comprising the same | KABUSHIKI KAISHA SHOFU (JP) | 2024-11-26 | — | — | US | disclosed |
| US-11866590-B2 | Diisocyanate-based radical polymerizable silane coupling compound having an urethane bond | KABUSHIKI KAISHA SHOFU (JP) | 2024-01-09 | — | — | US | disclosed |
| US-20220387264-A1 | DENTAL PHOTOCURABLE COMPOSITION EXCELLENT IN STORAGE STABILITY | SHOFU INC. (JP) | 2022-12-08 | — | — | US | disclosed |
| US-20220387264-A1 | DENTAL PHOTOCURABLE COMPOSITION EXCELLENT IN STORAGE STABILITY | SHOFU INC. (JP) | 2022-12-08 | — | — | US | disclosed |
| EP-4062893-A1 | DENTAL PHOTOCURABLE COMPOSITION EXCELLENT IN STORAGE STABILITY | Shofu Inc. (JP) | 2022-09-28 | — | — | EP | disclosed |
| US-20210395532-A1 | DIISOCYANATE-BASED RADICAL POLYMERIZABLE SILANE COUPLING COMPOUND HAVING AN URETHANE BOND | KABUSHIKI KAISHA SHOFU (JP) | 2021-12-23 | — | — | US | disclosed |
| US-20210395532-A1 | DIISOCYANATE-BASED RADICAL POLYMERIZABLE SILANE COUPLING COMPOUND HAVING AN URETHANE BOND | KABUSHIKI KAISHA SHOFU (JP) | 2021-12-23 | — | — | US | disclosed |
| CN-112771057-A | Diisocyanate-based radical-polymerizable silane coupling compound having urethane bond | 株式会社松风 | 2021-05-07 | — | — | CN | disclosed |
| US-20210122770-A1 | SILANE COUPLING COMPOUNDS AND MEDICAL AND/OR DENTAL CURABLE COMPOSITIONS COMPRISING THE SAME | KABUSHIKI KAISHA SHOFU (JP) | 2021-04-29 | — | — | US | disclosed |
| US-20210122770-A1 | SILANE COUPLING COMPOUNDS AND MEDICAL AND/OR DENTAL CURABLE COMPOSITIONS COMPRISING THE SAME | KABUSHIKI KAISHA SHOFU (JP) | 2021-04-29 | — | — | US | disclosed |
| US-10975229-B2 | Silane coupling compounds and medical and/or dental curable compositions comprising the same | KABUSHIKI KAISHA SHOFU (JP) | 2021-04-13 | — | — | US | disclosed |
| US-10975229-B2 | Silane coupling compounds and medical and/or dental curable compositions comprising the same | KABUSHIKI KAISHA SHOFU (JP) | 2021-04-13 | — | — | US | disclosed |
| US-20190300552-A1 | SILANE COUPLING COMPOUNDS AND MEDICAL AND/OR DENTAL CURABLE COMPOSITIONS COMPRISING THE SAME | KABUSHIKI KAISHA SHOFU (JP) | 2019-10-03 | — | — | US | disclosed |
| US-20190300552-A1 | SILANE COUPLING COMPOUNDS AND MEDICAL AND/OR DENTAL CURABLE COMPOSITIONS COMPRISING THE SAME | KABUSHIKI KAISHA SHOFU (JP) | 2019-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220387264-A1 | DENTAL PHOTOCURABLE COMPOSITION EXCELLENT IN STORAGE STABILITY | H1-0, POLA1, H1-2 | TSHR 3238/4885ACHE 2003/4885THRB 3906/4885 |
| US-20210122770-A1 | SILANE COUPLING COMPOUNDS AND MEDICAL AND/OR DENTAL CURABLE COMPOSITIONS COMPRISING THE SAME | SMCHD1, CAD, EPM2A | TSHR 2902/4885ACHE 3391/4885THRB 3383/4885 |
| US-11866590-B2 | Diisocyanate-based radical polymerizable silane coupling compound having an urethane bond | CAD, DCLRE1A, STIM1 | TSHR 4002/4885ACHE 2993/4885THRB 3954/4885 |
| US-10975229-B2 | Silane coupling compounds and medical and/or dental curable compositions comprising the same | SMCHD1, CAD, EPM2A | TSHR 2902/4885ACHE 3391/4885THRB 3383/4885 |
| US-12152045-B2 | Silane coupling compounds and medical and/or dental curable compositions comprising the same | SMCHD1, CAD, EPM2A | TSHR 2902/4885ACHE 3391/4885THRB 3383/4885 |
| US-20190300552-A1 | SILANE COUPLING COMPOUNDS AND MEDICAL AND/OR DENTAL CURABLE COMPOSITIONS COMPRISING THE SAME | SMCHD1, CAD, EPM2A | TSHR 2902/4885ACHE 3391/4885THRB 3383/4885 |
| US-20210395532-A1 | DIISOCYANATE-BASED RADICAL POLYMERIZABLE SILANE COUPLING COMPOUND HAVING AN URETHANE BOND | CAD, DCLRE1A, STIM1 | TSHR 4002/4885ACHE 2993/4885THRB 3954/4885 |
| US-20260083642-A1 | DENTAL COMPOSITION | TAS2R42, COL2A1, TAS2R1 | TSHR 1588/4885ACHE 4474/4885THRB 1557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.