Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9715006 | 0.90 | THRB (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9715028 | 0.87 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL35511 | 0.85 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL35807 | 0.85 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL214065 | 0.85 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12094871 | 0.85 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL35612 | 0.85 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5701562 | 0.84 | TSHR (0.45) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5701553 | 0.84 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL395578 | 0.83 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025022004-A2 | OPHTHALMIC LENS | CONTAMAC LIMITED (GB) | 2025-01-30 | — | — | WO | claimed |
| EP-0242080-B1 | COPOLYMER COMPOSITIONS | PARAGON OPTICAL INC (US) | 1992-12-16 | — | — | EP | claimed |
| EP-0242080-A2 | Copolymer compositions | PARAGON OPTICAL INC (US) | 1987-10-21 | — | — | EP | claimed |
| US-4661573-A | INTRAOCULAR AND CONTACT LENSES; COPOLYMER OF PERFLUROALKYL ACRYLATE, ACRYLOXYALKYLPOLYSILOXANE, ACRYLOXYALKYLSILANOL, POLYACRYLOXYALKYLPOLYSILOXANE | PARAGON OPTICAL INC. (US) | 1987-04-28 | — | — | US | claimed |
| EP-2926967-B1 | SILICONE HYDROGEL CONTACT LENS HAVING HYDROPHILIC SURFACE | HOYA CORP (JP) | 2025-10-08 | — | — | EP | disclosed |
| WO-2025022004-A2 | OPHTHALMIC LENS | CONTAMAC LIMITED (GB) | 2025-01-30 | — | — | WO | disclosed |
| CN-117487307-A | ABS composite antibacterial plastic and preparation method and application thereof | 育才控股集团股份有限公司 | 2024-02-02 | — | — | CN | disclosed |
| US-10241234-B2 | Silicone hydrogel soft contact lens having wettable surface | HOYA CORPORATION (JP) | 2019-03-26 | — | — | US | disclosed |
| US-9529119-B2 | Method for fabricating silicone-containing copolymer molded article having hydrophilic surface and silicone-hydrogel contact lens having hydrophilic surface | HOYA CORPORATION (JP) | 2016-12-27 | — | — | US | disclosed |
| US-20160282516-A1 | METHOD FOR FABRICATING SILICONE-CONTAINING COPOLYMER MOLDED ARTICLE HAVING HYDROPHILIC SURFACE AND SILICONE-HYDROGEL CONTACT LENS HAVING HYDROPHILIC SURFACE | HOYA CORPORATION (JP) | 2016-09-29 | — | — | US | disclosed |
| EP-2840431-B1 | SILICONE HYDROGEL SOFT CONTACT LENS HAVING WETTABLE SURFACE | HOYA CORP (JP) | 2016-09-07 | — | — | EP | disclosed |
| EP-2845708-B1 | METHOD FOR PRODUCING SILICONE-CONTAINING COPOLYMER MOLDED ARTICLE HAVING HYDROPHILIC SURFACE, AND SILICONE HYDROGEL CONTACT LENS HAVING HYDROPHILIC SURFACE | HOYA CORP (JP) | 2016-07-06 | — | — | EP | disclosed |
| EP-0209597-A1 | EXTENDED-WEAR LENSES | Bausch & Lomb Incorporated (US) | 1987-01-28 | — | — | EP | disclosed |
| EP-0192683-A1 | LENS COMPOSITION, ARTICLE AND METHOD OF MANUFACTURE. | PARAGON OPTICAL INC (US) | 1986-09-03 | — | — | EP | disclosed |
| WO-1986004343-A1 | EXTENDED-WEAR LENSES | BAUSCH AND LOMB INCORPORATED (US) | 1986-07-31 | — | — | WO | disclosed |
| EP-0184924-A2 | Lens composition, articles and method of manufacture | PARAGON OPTICAL INC (US) | 1986-06-18 | — | — | EP | disclosed |
| US-4582884-A | Lens composition, article and method of manufacture | PARAGON OPTICAL, INC. (US) | 1986-04-15 | — | — | US | disclosed |
| WO-1986001518-A1 | LENS COMPOSITION, ARTICLE AND METHOD OF MANUFACTURE | PARAGON OPTICAL, INC. (US) | 1986-03-13 | — | — | WO | disclosed |
| US-4535138-A | Silane ester contact lens composition, article and method of manufacture | PARAGON OPTICAL, INC. (US) | 1985-08-13 | — | — | US | disclosed |
| US-4419505-A | HYDROXYSILYLALKYL (METH)ACRYLATE COPOLYMER | PARAGON OPTICAL, INC. (US) | 1983-12-06 | — | — | US | disclosed |