Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 10/20 | 0.48 |
| ▸ | MMP9 | P14780 | 7/20 | 0.48 |
| ▸ | MMP8 | P22894 | 6/20 | 0.48 |
| ▸ | MMP1 | P03956 | 10/20 | 0.41 |
| ▸ | MMP3 | P08254 | 7/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | MMP7 | P09237 | 2/20 | 0.36 |
| ▸ | FCER2 | P06734 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22915324 | 0.80 | FFAR2 (0.32) | — | |
| SCHEMBL24923981 | 0.78 | MMP1 (0.35) | MMP9MMP1 | |
| SCHEMBL14546925 | 0.75 | MMP9 (0.37) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL28364562 | 0.75 | MMP2 (0.56) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL18762548 | 0.75 | MMP2 (0.56) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL21895921 | 0.73 | MMP2 (0.58) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL18048547 | 0.71 | MMP2 (0.36) | MMP2MMP9MMP8MMP1 | |
| SCHEMBL18048546 | 0.71 | MMP2 (0.36) | MMP2MMP9MMP8MMP1 | |
| SCHEMBL23520330 | 0.71 | ALDH1A1 (0.64) | MMP2MMP9MMP8MMP1MMP3 | |
| SCHEMBL14198796 | 0.71 | ALDH1A1 (0.64) | MMP2MMP9MMP8MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3545974-A1 | MEDICAL USE OF ANTI-C MET ANTIBODY-CYTOTOXIC DRUG CONJUGATE | Suzhou Suncadia Biopharmaceuticals Co., Ltd. (CN) | 2019-10-02 | — | — | EP | disclosed |