SCHEMBL21422239

SCHEMBL21422239

CC(c1ccc2c(Cl)nccc2c1)C1CCCC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 8/20 0.40
SLC6A2 P23975 4/20 0.40
SLC6A4 P31645 4/20 0.40
MAPK1 P28482 2/20 0.35
KMT5B Q4FZB7 2/20 0.35
KMT5C Q86Y97 2/20 0.35
JAK3 P52333 2/20 0.33
LMNA P02545 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33
APEX1 P27695 1/20 0.33
PMP22 Q01453 1/20 0.33
IRAK4 Q9NWZ3 1/20 0.32
GRM4 Q14833 1/20 0.32
PARG Q86W56 1/20 0.32
HIPK2 Q9H2X6 1/20 0.32
IDO1 P14902 1/20 0.31
CHEK1 O14757 1/20 0.31
NTRK1 P04629 1/20 0.31
FYN P06241 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30978865 1.00 SLC6A3 (0.40) SLC6A3SLC6A2SLC6A4MAPK1KMT5B
SCHEMBL22170802 0.79 LMNA (0.40) MAPK1LMNACYP3A4MAPTAPEX1
SCHEMBL21422240 0.78 MAPK1 (0.38) SLC6A3SLC6A2SLC6A4MAPK1JAK3
SCHEMBL21864503 0.77 MAPK1 (0.40) SLC6A3SLC6A2SLC6A4MAPK1JAK3
SCHEMBL30532199 0.74 ALDH1A1 (0.38) MAPK1LMNACYP3A4MAPTAPEX1
SCHEMBL21405686 0.74 ALDH1A1 (0.38) MAPK1LMNACYP3A4MAPTAPEX1
SCHEMBL24157581 0.73 MAPK1 (0.32) MAPK1
SCHEMBL21785111 0.72 AKT1 (0.46) SLC6A3SLC6A2SLC6A4ROCK1
SCHEMBL26928633 0.72 ROCK1 (0.38) IRAK4ROCK1
SCHEMBL21444760 0.72 MAPK1 (0.33) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111004287-B Organometallic compound and organic light emitting device including the same 三星电子株式会社 2024-07-02 CN disclosed
US-11827648-B2 Organometallic compound, organic light-emitting device including the same, and diagnostic composition including the organometallic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-11-28 US disclosed
US-11827648-B2 Organometallic compound, organic light-emitting device including the same, and diagnostic composition including the organometallic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-11-28 US disclosed
US-11827649-B2 Organometallic compound, organic light-emitting device including the same, and diagnostic composition including the organometallic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-11-28 US disclosed
US-11827649-B2 Organometallic compound, organic light-emitting device including the same, and diagnostic composition including the organometallic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-11-28 US disclosed
US-20220411450-A1 ORGANOMETALLIC COMPOUND, ORTGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO LTD (KR) 2022-12-29 US disclosed
US-11459348-B2 Organometallic compound, organic light-emitting device including the same, and diagnostic composition including the organometallic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-10-04 US disclosed
US-20220029112-A1 ORGANOMETALLIC COMPOUND, ORTGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO LTD (KR) 2022-01-27 US disclosed
EP-3549944-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO LTD (KR) 2021-12-29 EP disclosed
EP-3637489-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Samsung Electronics Co., Ltd. (KR) 2020-04-15 EP disclosed
CN-111004287-A Organometallic compound and organic light emitting device including the same 三星电子株式会社 2020-04-14 CN disclosed
US-20200111977-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-04-09 US disclosed
US-20200111977-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-04-09 US disclosed
US-20190300557-A1 ORGANOMETALLIC COMPOUND, ORTGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-10-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11459348-B2 Organometallic compound, organic light-emitting device including the same, and diagnostic composition including the organometallic compound ORC3, MCM6, LEF1 SLC6A3 4356/4885SLC6A2 4502/4885SLC6A4 4544/4885
US-11827649-B2 Organometallic compound, organic light-emitting device including the same, and diagnostic composition including the organometallic compound ORC3, MCM6, LEF1 SLC6A3 4356/4885SLC6A2 4502/4885SLC6A4 4544/4885
US-20220029112-A1 ORGANOMETALLIC COMPOUND, ORTGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND ORC3, ORMDL3, OR10J3 SLC6A3 4015/4885SLC6A2 4374/4885SLC6A4 4341/4885
US-20190300557-A1 ORGANOMETALLIC COMPOUND, ORTGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND ORC3, ORMDL3, OR10J3 SLC6A3 4015/4885SLC6A2 4374/4885SLC6A4 4341/4885
US-11827648-B2 Organometallic compound, organic light-emitting device including the same, and diagnostic composition including the organometallic compound ORC3, MCM6, LEF1 SLC6A3 4356/4885SLC6A2 4502/4885SLC6A4 4544/4885
US-20220411450-A1 ORGANOMETALLIC COMPOUND, ORTGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND ORC3, ORMDL3, OR10J3 SLC6A3 4015/4885SLC6A2 4374/4885SLC6A4 4341/4885
US-20200111977-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME ORC3, ORMDL3, OR10J3 SLC6A3 3816/4885SLC6A2 4483/4885SLC6A4 4243/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.