SCHEMBL22170802

SCHEMBL22170802

CC(C)c1ccc2c(Cl)nccc2c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.40
CYP3A4 P08684 1/20 0.40
MAPT P10636 1/20 0.40
APEX1 P27695 1/20 0.40
MAPK1 P28482 1/20 0.40
PMP22 Q01453 1/20 0.40
MAP4K4 O95819 2/20 0.38
TBK1 Q9UHD2 2/20 0.38
AURKA O14965 1/20 0.38
DAPK3 O43293 1/20 0.38
JAK2 O60674 1/20 0.38
PAK4 O96013 1/20 0.38
ABL1 P00519 1/20 0.38
LCK P06239 1/20 0.38
FYN P06241 1/20 0.38
CSF1R P07333 1/20 0.38
RET P07949 1/20 0.38
IGF1R P08069 1/20 0.38
FLT1 P17948 1/20 0.38
LTK P29376 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26910255 0.86 LMNA (0.43) LMNACYP3A4MAPTAPEX1MAPK1
SCHEMBL21405686 0.83 ALDH1A1 (0.38) LMNACYP3A4MAPTAPEX1MAPK1
SCHEMBL30532199 0.83 ALDH1A1 (0.38) LMNACYP3A4MAPTAPEX1MAPK1
SCHEMBL10024935 0.80 LMNA (0.41) LMNAMAPTMAP4K4TBK1AURKA
SCHEMBL10057582 0.80 CYP2A6 (0.50) LMNAMAP4K4TBK1AURKADAPK3
SCHEMBL26928427 0.79 ACHE (0.38) LMNACYP3A4MAPTAPEX1MAPK1
SCHEMBL30978865 0.79 SLC6A3 (0.40) LMNACYP3A4MAPTAPEX1MAPK1
SCHEMBL21422239 0.79 SLC6A3 (0.40) LMNACYP3A4MAPTAPEX1MAPK1
SCHEMBL12546016 0.79 ROCK1 (0.53) MAP4K4TBK1AURKADAPK3JAK2
SCHEMBL26497718 0.79 TBK1 (0.38) LMNAMAPTMAP4K4TBK1AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114989224-B Metal complex, organic electroluminescent element and consumer product 上海八亿时空先进材料有限公司 2024-10-29 CN disclosed
WO-2023239645-A1 SMARCA DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. (US) 2023-12-14 WO disclosed
US-20230309373-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-09-28 US disclosed
US-20230309373-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-09-28 US disclosed
US-20230295204-A1 METAL COMPLEX AND USE THEREOF GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD (CN) 2023-09-21 US disclosed
US-20230295204-A1 METAL COMPLEX AND USE THEREOF GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD (CN) 2023-09-21 US disclosed
US-20230227485-A1 METAL IRIDIUM COMPLEX AND USE THEREOF GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD (CN) 2023-07-20 US disclosed
US-20230227485-A1 METAL IRIDIUM COMPLEX AND USE THEREOF GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD (CN) 2023-07-20 US disclosed
US-20230200207-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-22 US disclosed
US-20230200207-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-22 US disclosed
US-20230130284-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-04-27 US disclosed
US-20230130284-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-04-27 US disclosed
US-20230124167-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-04-20 US disclosed
US-20230123928-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-04-20 US disclosed
WO-2022262309-A1 ORGANOMETALLIC IRIDIUM COMPOUND AND APPLICATION THEREOF 广东阿格蕾雅光电材料有限公司 2022-12-22 WO disclosed
US-20220127288-A1 ORGANIC METAL COMPOUND, ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE HAVING THE COMPOUND LG DISPLAY CO., LTD. (KR) 2022-04-28 US disclosed
EP-3988556-A1 ORGANIC METAL COMPOUND, ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE HAVING THE COMPOUND LG Display Co., Ltd. (KR) 2022-04-27 EP disclosed
US-20220115603-A1 ORGANIC METAL COMPOUND AND APPLICATION THEREOF GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD (CN) 2022-04-14 US disclosed
WO-2021258875-A1 METAL IRIDIUM COMPLEX AND USE THEREOF 广东阿格蕾雅光电材料有限公司 2021-12-30 WO disclosed
WO-2020134570-A1 ORGANIC METAL COMPOUND AND APPLICATION THEREOF 广东阿格蕾雅光电材料有限公司 2020-07-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230295204-A1 METAL COMPLEX AND USE THEREOF IK, CYBA, LAS1L LMNA 670/4885CYP3A4 2233/4885MAPT 1138/4885
US-20230130284-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME PPOX, PER2, CRY1 LMNA 1537/4885CYP3A4 856/4885MAPT 528/4885
US-20220127288-A1 ORGANIC METAL COMPOUND, ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE HAVING THE COMPOUND OCIAD1, OCIAD2, OXA1L LMNA 3115/4885CYP3A4 232/4885MAPT 427/4885
US-20220115603-A1 ORGANIC METAL COMPOUND AND APPLICATION THEREOF TRPM2, TRPM5, TRPM4 LMNA 1521/4885CYP3A4 784/4885MAPT 521/4885
US-20230227485-A1 METAL IRIDIUM COMPLEX AND USE THEREOF IK, INTS9, CYBA LMNA 3025/4885CYP3A4 1506/4885MAPT 652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.