Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ORAI1 | Q96D31 | 3/20 | 0.39 |
| ▸ | ORAI2 | Q96SN7 | 3/20 | 0.39 |
| ▸ | ORAI3 | Q9BRQ5 | 3/20 | 0.39 |
| ▸ | TRPV6 | Q9H1D0 | 3/20 | 0.39 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28821752 | 0.81 | CYP3A4 (0.38) | CYP3A4ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL11904863 | 0.80 | ORAI1 (0.39) | CYP3A4ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL28545103 | 0.80 | ORAI1 (0.39) | CYP3A4ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL2143304 | 0.79 | CYP3A4 (0.38) | CYP3A4ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL9941405 | 0.77 | TRPV6 (0.37) | CYP3A4ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL9941370 | 0.74 | AKT1 (0.40) | ORAI1ORAI2ORAI3TRPV6PCSK9 | |
| SCHEMBL363448 | 0.74 | TRPV6 (0.46) | CYP3A4ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL7568394 | 0.73 | CYP3A4 (0.38) | CYP3A4TSHRALDH1A1HSD17B10HPGD | |
| SCHEMBL1129435 | 0.72 | TRPV6 (0.44) | CYP3A4ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL1660275 | 0.72 | TRPV6 (0.44) | CYP3A4ORAI1ORAI2ORAI3TRPV6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116426295-A | Preparation method of side fluorine-containing terphenyl liquid crystal monomer | 河北凡克新材料有限公司 | 2023-07-14 | — | — | CN | claimed |
| CN-112898133-B | Preparation method of trans-ketone intermediate | 河北迈尔斯通电子材料有限公司 | 2022-11-15 | — | — | CN | claimed |
| CN-112850685-B | Two-dimensional carbon material and preparation method and application thereof | 厦门稀土材料研究所 | 2022-10-18 | — | — | CN | claimed |
| CN-113278094-B | Cyclodextrin derivative and preparation method and application thereof | 兰州大学 | 2022-03-01 | — | — | CN | claimed |
| CN-113278094-A | Cyclodextrin derivative and preparation method and application thereof | 兰州大学 | 2021-08-20 | — | — | CN | claimed |
| CN-108753312-B | Liquid crystal compound, preparation method thereof, composition containing liquid crystal compound and high-frequency component containing liquid crystal medium | 西安近代化学研究所 | 2021-07-27 | — | — | CN | claimed |
| CN-112898133-A | Preparation method of trans-ketone intermediate | 河北迈尔斯通电子材料有限公司 | 2021-06-04 | — | — | CN | claimed |
| CN-117865773-A | Preparation method of difluoromethyl aromatic compound based on palladium-catalyzed decarbonylation coupling | 大连理工大学 | 2024-04-12 | — | — | CN | disclosed |
| CN-116426295-A | Preparation method of side fluorine-containing terphenyl liquid crystal monomer | 河北凡克新材料有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-112898133-B | Preparation method of trans-ketone intermediate | 河北迈尔斯通电子材料有限公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-112850685-B | Two-dimensional carbon material and preparation method and application thereof | 厦门稀土材料研究所 | 2022-10-18 | — | — | CN | disclosed |
| CN-113278094-B | Cyclodextrin derivative and preparation method and application thereof | 兰州大学 | 2022-03-01 | — | — | CN | disclosed |
| CN-113278094-A | Cyclodextrin derivative and preparation method and application thereof | 兰州大学 | 2021-08-20 | — | — | CN | disclosed |
| US-20080293768-A1 | Novel Compounds Derived From 5-Thioxylose And Their Use In Therapeutics | INVENTIVA (FR) | 2008-11-27 | — | — | US | disclosed |
| EP-1414955-B1 | COMPOSITIONS FOR ENHANCED CATALYZED REPORTER DEPOSITION | PERKINELMER LIFE SCIENCES INC (US) | 2008-08-20 | — | — | EP | disclosed |
| EP-1414955-A4 | COMPOSITIONS FOR ENHANCED CATALYZED REPORTER DEPOSITION | PERKINELMER LIFE SCIENCES INC (US) | 2004-10-06 | — | — | EP | disclosed |
| EP-1414955-A2 | COMPOSITIONS FOR ENHANCED CATALYZED REPORTER DEPOSITION | Perkinelmer Life Sciences, Inc. (US) | 2004-05-06 | — | — | EP | disclosed |
| US-6617125-B2 | Reacting conjugate comprising detectably labeled phenol-containing molecule with peroxidase enzyme; for detection of cytomegalovirus using cyanide-3 tyramide enhanced with 4-thioanisole boronic acid | PERKINELMER LIFE SCIENCES, INC. | 2003-09-09 | — | — | US | disclosed |
| US-20030017460-A1 | Compositions for enhanced catalyzed reporter deposition | PERKINELMER LIFE SCIENCES, INC. | 2003-01-23 | — | — | US | disclosed |
| WO-2003002733-A2 | COMPOSITIONS FOR ENHANCED CATALYZED REPORTER DEPOSITION | PERKINELMER LIFE SCIENCES, INC. (US) | 2003-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293768-A1 | Novel Compounds Derived From 5-Thioxylose And Their Use In Therapeutics | TPMT, STS, TBXAS1 | CYP3A4 256/4885ORAI1 4387/4885ORAI2 4583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.