Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 2/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 4/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | PIK3C2A | O00443 | 1/20 | 0.30 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21434183 | 0.88 | DRD2 (0.32) | ALDH1A1DRD2DRD3CYP1A2 | |
| SCHEMBL31686852 | 0.88 | DRD2 (0.32) | ALDH1A1DRD2DRD3CYP1A2 | |
| SCHEMBL29904936 | 0.85 | POLB (0.39) | ALDH1A1KCNH2TRPM8DDR1 | |
| SCHEMBL17844096 | 0.85 | POLB (0.39) | ALDH1A1KCNH2TRPM8DDR1 | |
| SCHEMBL17529566 | 0.85 | S1PR1 (0.32) | PIK3C2APIK3C2BPIK3CAMTOR | |
| SCHEMBL17609373 | 0.83 | POLB (0.37) | ALDH1A1KCNH2TRPM8DDR1 | |
| SCHEMBL23120240 | 0.82 | — | — | |
| SCHEMBL29748688 | 0.82 | — | — | |
| SCHEMBL17858042 | 0.82 | POLB (0.38) | ALDH1A1TRPM8DDR1 | |
| SCHEMBL23120278 | 0.82 | LMNA (0.38) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11072608-B2 | Pesticidally active heterocyclic derivatives with sulphur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2021-07-27 | — | — | US | disclosed |
| US-20190308971-A1 | PESTICIDALLY ACTIVE HETROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11072608-B2 | Pesticidally active heterocyclic derivatives with sulphur containing substituents | DDT, ACHE, GSTM1 | ALDH1A1 242/4885KCNH2 1533/4885IDH1 169/4885 |
| US-20190308971-A1 | PESTICIDALLY ACTIVE HETROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | DDT, GSTO1, GSTM1 | ALDH1A1 490/4885KCNH2 1989/4885IDH1 826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.