Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Dodecanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 2/20 | 0.93 |
| ▸ | THRB known ✓ | P10828 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.93 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.93 |
| ▸ | TSHR | P16473 | 3/20 | 0.93 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.93 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.93 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.86 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octanol SCHEMBL29030807 | 1.00 | LMNA (0.93) | LMNAALDH1A1TSHRMEN1KMT2A | |
| 1-Hexanol SCHEMBL2847264 | 1.00 | — | — | |
| Tridecan-1-Ol SCHEMBL17318161 | 1.00 | LMNA (0.93) | LMNAALDH1A1TSHRMEN1KMT2A | |
| 1-Hexanol SCHEMBL7552478 | 1.00 | LMNA (0.93) | LMNAALDH1A1TSHRMEN1KMT2A | |
| Cetyl Alcohol SCHEMBL10809721 | 1.00 | LMNA (0.93) | LMNAALDH1A1TSHRMEN1KMT2A | |
| 1-Heptanol SCHEMBL437066 | 1.00 | — | — | |
| 1-Hexanol SCHEMBL10524091 | 1.00 | LMNA (0.93) | LMNAALDH1A1TSHRMEN1KMT2A | |
| 1-Hexanol SCHEMBL7138712 | 1.00 | LMNA (0.93) | LMNAALDH1A1TSHRMEN1KMT2A | |
| Octanol SCHEMBL20527756 | 1.00 | LMNA (0.93) | LMNAALDH1A1TSHRMEN1KMT2A | |
| Octanol SCHEMBL30740443 | 1.00 | LMNA (0.93) | LMNAALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104086092-B | A kind of Superhydrophilic self-cleaning antifog laminated film and preparation method thereof and application | 华南理工大学 | 2016-06-22 | — | — | CN | claimed |
| CN-104086092-A | Super-hydrophilic self-cleaning antifogging composite film, and preparation method and application thereof | UNIV SOUTH CHINA TECH | 2014-10-08 | — | — | CN | claimed |
| CN-101643214-A | Preparation method of super-hydrophilic mesoporous silicon oxide films | UNIV SOUTH CHINA TECH | 2010-02-10 | — | — | CN | claimed |
| CN-111364602-A | Building composition of ecological city | 几何智慧城市科技(广州)有限公司 | 2020-07-03 | — | — | CN | disclosed |
| US-10654765-B2 | Method for producing a latent heat storage material and dialkyl ether as a latent heat storage material | SASOL GERMANY GMBH (DE) | 2020-05-19 | — | — | US | disclosed |
| US-20160257628-A1 | Method for Producing a Latent Heat Storage Material and Dialkyl Ether as a Latent Heat Storage Material | SASOL GERMANY GMBH | 2016-09-08 | — | — | US | disclosed |
| CN-104086092-B | A kind of Superhydrophilic self-cleaning antifog laminated film and preparation method thereof and application | 华南理工大学 | 2016-06-22 | — | — | CN | disclosed |
| CN-104086092-A | Super-hydrophilic self-cleaning antifogging composite film, and preparation method and application thereof | UNIV SOUTH CHINA TECH | 2014-10-08 | — | — | CN | disclosed |
| CN-101643214-B | Preparation method of super-hydrophilic mesoporous silicon oxide films | UNIV SOUTH CHINA TECH | 2011-09-07 | — | — | CN | disclosed |
| CN-101190917-B | 3,4-dihydro-3-methyl-4-oxomidazo[5,1-d]-1,2,3,5-tetrazine-8-formic acid benzenesulfonyl furoxan esters compound, preparation method and use thereof | TIANJIN TASLY GROUP CO LTD | 2011-07-13 | — | — | CN | disclosed |
| US-20110056656-A1 | Method for Producing a Latent Heat Storage Material and Dialkyl Ether as a Latent Heat Storage Material | ZIEHE HOLGER | 2011-03-10 | — | — | US | disclosed |
| CN-101643214-A | Preparation method of super-hydrophilic mesoporous silicon oxide films | UNIV SOUTH CHINA TECH | 2010-02-10 | — | — | CN | disclosed |
| CN-101190917-A | 3,4-dihydro-3-methyl-4-oxomidazo[5,1-d]-1,2,3,5-tetrazine-8-formic acid benzenesulfonyl furoxan esters compound, preparation method and use thereof | TIANJIN TASLY GROUP CO LTD (CN) | 2008-06-04 | — | — | CN | disclosed |
| US-4719194-A | STORAGE STABILITY | GENERAL ELECTRIC COMPANY (US) | 1988-01-12 | — | — | US | disclosed |