Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HK1 | P19367 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GALK1 | P51570 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1973489 | 0.75 | AHR (0.45) | MAPTNPC1AHRPDK2MAPK1 | |
| SCHEMBL61132 | 0.75 | AHR (0.50) | MAPTNPC1KDM4EMEN1KMT2A | |
| SCHEMBL9630603 | 0.74 | — | — | |
| SCHEMBL2144679 | 0.74 | — | — | |
| Acridan SCHEMBL183367 | 0.69 | MAPT (0.65) | MAPTNPC1KDM4EMEN1KMT2A | |
| SCHEMBL577541 | 0.69 | GAA (0.43) | MAPTNPC1KDM4EMEN1KMT2A | |
| Acridan SCHEMBL29405807 | 0.69 | MAPT (0.65) | MAPTNPC1KDM4EMEN1KMT2A | |
| SCHEMBL407439 | 0.69 | NPC1 (0.70) | MAPTNPC1KDM4EMEN1KMT2A | |
| SCHEMBL21151025 | 0.69 | GAA (0.43) | MAPTNPC1KDM4EMEN1KMT2A | |
| Acridan SCHEMBL20594012 | 0.69 | MAPT (0.65) | MAPTNPC1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515991-B1 | PHOTOCHROMIC MULTIPLE RING-FUSED NAPHTHOPYRANS HAVING EXTREME LONGWAVE ABSORPTION EXTENDING FAR INTO THE VISIBLE WAVELENGTH RANGE | RODENSTOCK GMBH (DE) | 2020-10-07 | — | — | EP | claimed |
| US-10647852-B2 | Photochromic multiple ring-fused naphthopyrans having extreme longwave absorption extending far into the visible wavelength range | RODENSTOCK GMBH (DE) | 2020-05-12 | — | — | US | claimed |
| US-20190284397-A1 | PHOTOCHROMIC MULTIPLE RING-FUSED NAPHTHOPYRANS HAVING EXTREME LONGWAVE ABSORPTION EXTENDING FAR INTO THE VISIBLE WAVELENGTH RANGE | RODENSTOCK GMBH (DE) | 2019-09-19 | — | — | US | claimed |
| EP-3515991-A1 | PHOTOCHROMIC MULTIPLE RING-FUSED NAPHTHOPYRANS HAVING EXTREME LONGWAVE ABSORPTION EXTENDING FAR INTO THE VISIBLE WAVELENGTH RANGE | Rodenstock GmbH (DE) | 2019-07-31 | — | — | EP | claimed |
| US-10077274-B2 | UV-curing-compatible photochromic fused naphthopyrans | RODENSTOCK GMBH (DE) | 2018-09-18 | — | — | US | claimed |
| US-9963574-B2 | Photochromic fluorenopyrans with defined dibenzo[B,D]pyrano fused attachment | RODENSTOCK GMBH (DE) | 2018-05-08 | — | — | US | claimed |
| WO-2018054507-A1 | PHOTOCHROMIC MULTIPLE RING-FUSED NAPHTHOPYRANS HAVING EXTREME LONGWAVE ABSORPTION EXTENDING FAR INTO THE VISIBLE WAVELENGTH RANGE | RODENSTOCK GMBH (DE) | 2018-03-29 | — | — | WO | claimed |
| EP-3010924-B1 | PHOTOCHROMIC FUSED NAPHTHOPYRANES COMPATIBLE TO UV-CURING | RODENSTOCK GMBH (DE) | 2016-09-14 | — | — | EP | claimed |
| US-20160152629-A1 | UV-CURING-COMPATIBLE PHOTOCHROMIC FUSED NAPHTHOPYRANS | RODENSTOCK GMBH (DE) | 2016-06-02 | — | — | US | claimed |
| EP-2872517-B1 | PHOTOCHROMIC FLUORENOPYRANS WITH DEFINED DIBENZO[B,D]PYRANO FUSED ATTACHMENT | RODENSTOCK GMBH (DE) | 2016-04-27 | — | — | EP | claimed |
| US-20100243971-A1 | PHOTOCHROMIC BENZOPYRANS | RODENSTOCK GMBH (DE) | 2010-09-30 | — | — | US | claimed |
| EP-2215526-A1 | PHOTOCHROMIC BENZOPYRANES | Rodenstock GmbH (DE) | 2010-08-11 | — | — | EP | claimed |
| EP-2178883-A1 | PHOTOCHROMIC BENZOPYRANO-BENZOPYRANS WITH FURTHER FUSING | Rodenstock GmbH (DE) | 2010-04-28 | — | — | EP | claimed |
| EP-1945625-B1 | PHOTOCHROMIC SPIRODIHYDROPHENANTHROPYRANS | RODENSTOCK GMBH (DE) | 2010-03-03 | — | — | EP | claimed |
| WO-2009132842-A1 | PHOTOCHROMIC NAPHTHOPYRANES HAVING A DOUBLE-BRIDGED TERPHENYL SUB-UNIT | RODENSTOCK GMBH (DE) | 2009-11-05 | — | — | WO | claimed |
| WO-2009068247-A1 | PHOTOCHROMIC BENZOPYRANES | RODENSTOCK GMBH (DE) | 2009-06-04 | — | — | WO | claimed |
| WO-2009024271-A1 | PHOTOCHROMIC BENZOPYRANO-BENZOPYRANS WITH FURTHER FUSING | RODENSTOCK GMBH (DE) | 2009-02-26 | — | — | WO | claimed |
| US-20080262248-A1 | Photochromic Spirodihydrophenanthropyrans | RODENSTOCK GMBH (DE) | 2008-10-23 | — | — | US | claimed |
| EP-1945625-A1 | PHOTOCHROMIC SPIRODIHYDROPHENANTHROPYRANS | Rodenstock GmbH (DE) | 2008-07-23 | — | — | EP | claimed |
| WO-2007054240-A1 | PHOTOCHROMIC SPIRODIHYDROPHENANTHROPYRANS | RODENSTOCK GMBH (DE) | 2007-05-18 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10077274-B2 | UV-curing-compatible photochromic fused naphthopyrans | GNE, ALDH1A2, NQO1 | MAPT 594/4885NPC1 3206/4885KDM4E 1834/4885 |
| US-20100243971-A1 | PHOTOCHROMIC BENZOPYRANS | DDT, MITF, PDS5A | MAPT 323/4885NPC1 4811/4885KDM4E 1731/4885 |
| US-20160152629-A1 | UV-CURING-COMPATIBLE PHOTOCHROMIC FUSED NAPHTHOPYRANS | GNE, ALDH1A2, NQO1 | MAPT 594/4885NPC1 3206/4885KDM4E 1834/4885 |
| US-10647852-B2 | Photochromic multiple ring-fused naphthopyrans having extreme longwave absorption extending far into the visible wavelength range | IGLV6-57, PUF60, STRA6 | MAPT 757/4885NPC1 1002/4885KDM4E 3110/4885 |
| US-20080262248-A1 | Photochromic Spirodihydrophenanthropyrans | ALDH1A2, QDPR, RB1 | MAPT 1336/4885NPC1 3631/4885KDM4E 2700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.