Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | HPGD | P15428 | 6/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4396833 | 1.00 | TSHR (0.46) | TSHRCYP3A4ALDH1A1HPGDHSD17B10 | |
| SCHEMBL1191865 | 0.80 | TSHR (0.41) | TSHRCYP3A4ALDH1A1HPGDHSD17B10 | |
| SCHEMBL1385568 | 0.74 | CYP3A4 (0.40) | TSHRCYP3A4ALDH1A1HPGDHSD17B10 | |
| SCHEMBL2144679 | 0.74 | — | — | |
| SCHEMBL9630603 | 0.74 | — | — | |
| SCHEMBL1840524 | 0.70 | PARP1 (0.42) | TSHRCYP3A4ALDH1A1HPGDHSD17B10 | |
| SCHEMBL7548249 | 0.67 | MAOA (0.37) | TSHRALDH1A1HPGDCYP1A2KDM4E | |
| SCHEMBL7548244 | 0.67 | MAOA (0.37) | TSHRALDH1A1HPGDCYP1A2KDM4E | |
| SCHEMBL1663773 | 0.66 | ALDH1A1 (0.50) | TSHRCYP3A4ALDH1A1HPGDHSD17B10 | |
| Acenaphthene SCHEMBL3416108 | 0.66 | TSHR (0.57) | TSHRCYP3A4ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 481 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4399200-A1 | (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS | Mitsubishi Gas Chemical Company, Inc. (JP) | 2024-07-17 | — | — | EP | claimed |
| EP-4399199-A1 | (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS | Reuter Chemische Apparatebau e.K. (DE) | 2024-07-17 | — | — | EP | claimed |
| WO-2024115460-A1 | BINAPHTHYL COMPOUNDS AND THERMOPLASTIC RESINS | REUTER CHEMISCHE APPARATEBAU E.K. (DE) | 2024-06-06 | — | — | WO | claimed |
| US-11999723-B2 | Pyrazole-containing macrophage migration inhibitory factor inhibitors | YALE UNIVERSITY (US) | 2024-06-04 | — | — | US | claimed |
| CN-118043298-A | (Hetero) aryl-substituted bisphenol compound and thermoplastic resin | 罗伊特化学仪器制造公司 | 2024-05-14 | — | — | CN | claimed |
| CN-117940399-A | Heteroaryl or aryl substituted bisphenol compounds and thermoplastic resins | 三菱瓦斯化学株式会社 | 2024-04-26 | — | — | CN | claimed |
| US-20230391704-A1 | TRIARYLMETHANE COMPOUNDS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2023-12-07 | — | — | US | claimed |
| WO-2023208837-A1 | OLIGOMERIC BINAPHTHYL COMPOUNDS AND THERMOPLASTIC RESINS | REUTER CHEMISCHE APPARATEBAU E.K. (DE) | 2023-11-02 | — | — | WO | claimed |
| WO-2023210833-A1 | OLIGOMERIC BINAPHTYL COMPOUNDS AND THERMOPLASTIC RESINS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2023-11-02 | — | — | WO | claimed |
| US-20230322788-A1 | IMIDAZOTRIAZINE AND PYRROLOPYRIMIDINE DERIVATIVES AS KRAS G12C INHIBITORS | BEONE MEDICINES I GMBH (CH) | 2023-10-12 | — | — | US | claimed |
| CN-1919851-A | Organosiloxane compound and organic light-emitting device comprising the same | SAMSUNG SDI CO LTD (KR) | 2007-02-28 | — | — | CN | claimed |
| US-7173045-B2 | 4-aminomethyl-1-aryl-cyclohexylamine compounds | GRUENENTHAL GMBH (DE) | 2007-02-06 | — | — | US | claimed |
| WO-2006131519-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-12-14 | — | — | WO | claimed |
| US-20050245593-A1 | 4-Aminomethyl-1-aryl-cyclohexylamine compounds | GRUENENTHAL GMBH (DE) | 2005-11-03 | — | — | US | claimed |
| CN-1575269-A | Novel soluble compound and organic electroluminescent element | IDEMITSU KOSAN CO (JP) | 2005-02-02 | — | — | CN | claimed |
| EP-1144415-A2 | FUNCTIONALIZED HETEROCYCLES AS CHEMOKINE RECEPTOR MODULATORS | WARNER-LAMBERT COMPANY (US) | 2001-10-17 | — | — | EP | claimed |
| WO-2000042045-A2 | FUNCTIONALIZED HETEROCYCLES AS CHEMOKINE RECEPTOR MODULATORS | WARNER-LAMBERT COMPANY (US) | 2000-07-20 | — | — | WO | claimed |
| US-5312707-A | Compositions for images | RICOH COMPANY, LTD. (JP) | 1994-05-17 | — | — | US | claimed |
| WO-1992015579-A1 | MULTICYCLIC TERTIARY AMINE POLYAROMATIC SQUALENE SYNTHETASE INHIBITORS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-09-17 | — | — | WO | claimed |
| US-3971804-A | ACARICIDES, FUNGICIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11999723-B2 | Pyrazole-containing macrophage migration inhibitory factor inhibitors | MIF, MMP12, CSF1R | TSHR 4253/4885CYP3A4 2748/4885ALDH1A1 2824/4885 |
| US-20230391704-A1 | TRIARYLMETHANE COMPOUNDS | CBR3, HAX1, HRH3 | TSHR 1467/4885CYP3A4 113/4885ALDH1A1 2431/4885 |
| US-20050245593-A1 | 4-Aminomethyl-1-aryl-cyclohexylamine compounds | HNMT, PNMT, INMT | TSHR 1669/4885CYP3A4 39/4885ALDH1A1 718/4885 |
| US-20230322788-A1 | IMIDAZOTRIAZINE AND PYRROLOPYRIMIDINE DERIVATIVES AS KRAS G12C INHIBITORS | KRAS, NRAS, HRAS | TSHR 2616/4885CYP3A4 3094/4885ALDH1A1 3193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.