Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.43 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19066731 | 1.00 | CTSK (0.46) | CTSKCTSBCTSLCTSSAAK1 | |
| SCHEMBL18248083 | 1.00 | CTSK (0.46) | CTSKCTSBCTSLCTSSAAK1 | |
| SCHEMBL21447763 | 1.00 | CTSK (0.46) | CTSKCTSBCTSLCTSSAAK1 | |
| SCHEMBL18256324 | 1.00 | CTSK (0.46) | CTSKCTSBCTSLCTSSAAK1 | |
| SCHEMBL13519510 | 0.92 | CTSK (0.48) | CTSKCTSBCTSLCTSSAAK1 | |
| SCHEMBL27853178 | 0.92 | CTSK (0.48) | CTSKCTSBCTSLCTSSAAK1 | |
| SCHEMBL22651717 | 0.90 | CTSK (0.41) | CTSKCTSBCTSLCTSSAAK1 | |
| SCHEMBL23269885 | 0.89 | MMP13 (0.39) | CTSKCTSBCTSLCTSSREN | |
| SCHEMBL18248147 | 0.89 | MMP13 (0.39) | CTSKCTSBCTSLCTSSREN | |
| SCHEMBL18248145 | 0.89 | MMP13 (0.39) | CTSKCTSBCTSLCTSSREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3676265-B1 | METHOD FOR THE SYNTHESIS OF CYCLIC DEPSIPEPTIDES | ELANCO ANIMAL HEALTH GMBH (DE) | 2025-08-20 | — | — | EP | disclosed |
| EP-3790876-B1 | ENDOPARASITIC DEPSIPEPTIDES | ZOETIS SERVICES LLC (US) | 2025-04-30 | — | — | EP | disclosed |
| US-20250019360-A1 | METHOD FOR THE SYNTHESIS OF CYCLIC DEPSIPEPTIDES | ELANCO ANIMAL HEALTH GMBH (DE) | 2025-01-16 | — | — | US | disclosed |
| US-12122759-B2 | Method for the synthesis of cyclic depsipeptides | ELANCO ANIMAL HEALTH GMBH (DE) | 2024-10-22 | — | — | US | disclosed |
| US-11786575-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2023-10-17 | — | — | US | disclosed |
| US-11771738-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2023-10-03 | — | — | US | disclosed |
| US-20220323540-A1 | Endoparasitic Depsipeptides | ZOETIS SERVICES LLC | 2022-10-13 | — | — | US | disclosed |
| US-11382949-B2 | Anthelmintic depsipeptide compounds | Boehringer Ingelheim Animal Health USA Inc. (US) | 2022-07-12 | — | — | US | disclosed |
| US-11382949-B2 | Anthelmintic depsipeptide compounds | Boehringer Ingelheim Animal Health USA Inc. (US) | 2022-07-12 | — | — | US | disclosed |
| US-20220211802-A1 | Endoparasitic Depsipeptides | ZOETIS SERVICES LLC | 2022-07-07 | — | — | US | disclosed |
| US-11331369-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2022-05-17 | — | — | US | disclosed |
| US-20210130315-A1 | METHOD FOR THE SYNTHESIS OF CYCLIC DEPSIPEPTIDES | BAYER ANIMAL HEALTH GMBH (DE) | 2021-05-06 | — | — | US | disclosed |
| EP-3790876-A1 | ENDOPARASITIC DEPSIPEPTIDES | Zoetis Services LLC (US) | 2021-03-17 | — | — | EP | disclosed |
| EP-3717478-A1 | ENDOPARASITIC DEPSIPEPTIDES | Zoetis Services LLC (US) | 2020-10-07 | — | — | EP | disclosed |
| US-20200282016-A1 | Endoparasitic Depsipeptides | ZOETIS SERVICES LLC | 2020-09-10 | — | — | US | disclosed |
| EP-3676265-A1 | METHOD FOR THE SYNTHESIS OF CYCLIC DEPSIPEPTIDES | Bayer Animal Health GmbH (DE) | 2020-07-08 | — | — | EP | disclosed |
| WO-2019217449-A1 | ENDOPARASITIC DEPSIPEPTIDES | ZOETIS SERVICES LLC (US) | 2019-11-14 | — | — | WO | disclosed |
| US-20190307838-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2019-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210130315-A1 | METHOD FOR THE SYNTHESIS OF CYCLIC DEPSIPEPTIDES | DNPEP, NPEPPS, PREP | CTSK 669/4885CTSB 690/4885CTSL 799/4885 |
| US-11786575-B2 | Endoparasitic depsipeptides | VIP, PREP, NGLY1 | CTSK 518/4885CTSB 143/4885CTSL 75/4885 |
| US-20200282016-A1 | Endoparasitic Depsipeptides | VIP, PREP, NGLY1 | CTSK 518/4885CTSB 143/4885CTSL 75/4885 |
| US-11382949-B2 | Anthelmintic depsipeptide compounds | ENPP2, ROCK2, RRP12 | CTSK 1247/4885CTSB 526/4885CTSL 480/4885 |
| US-20220211802-A1 | Endoparasitic Depsipeptides | VIP, PREP, NGLY1 | CTSK 518/4885CTSB 143/4885CTSL 75/4885 |
| US-12122759-B2 | Method for the synthesis of cyclic depsipeptides | DNPEP, NPEPPS, PREP | CTSK 669/4885CTSB 690/4885CTSL 799/4885 |
| US-20250019360-A1 | METHOD FOR THE SYNTHESIS OF CYCLIC DEPSIPEPTIDES | DNPEP, NPEPPS, PREP | CTSK 669/4885CTSB 690/4885CTSL 799/4885 |
| US-11771738-B2 | Endoparasitic depsipeptides | VIP, PREP, VIPR1 | CTSK 537/4885CTSB 175/4885CTSL 64/4885 |
| US-20220323540-A1 | Endoparasitic Depsipeptides | VIP, PREP, VIPR1 | CTSK 537/4885CTSB 175/4885CTSL 64/4885 |
| US-11331369-B2 | Endoparasitic depsipeptides | VIP, PREP, NGLY1 | CTSK 518/4885CTSB 143/4885CTSL 75/4885 |
| US-20190307838-A1 | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | ENPP2, ROCK2, RRP12 | CTSK 1247/4885CTSB 526/4885CTSL 480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.