Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 2/20 | 0.71 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.71 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.71 |
| ▸ | CDK2 | P24941 | 2/20 | 0.71 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.58 |
| ▸ | PI4KA | P42356 | 2/20 | 0.58 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.58 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.58 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.50 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.50 |
| ▸ | AHCY | P23526 | 3/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24980488 | 0.87 | ADORA2A (0.60) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL21128125 | 0.83 | CDK1 (0.50) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL8767031 | 0.83 | CCNE1 (1.00) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL12724436 | 0.83 | CDK1 (0.53) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL5161756 | 0.81 | CDK1 (0.73) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL15354451 | 0.81 | CDK1 (0.73) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL21504451 | 0.81 | CCNE1 (0.46) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL3440998 | 0.80 | CDK1 (0.71) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL26349135 | 0.80 | CDK1 (0.71) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL5999274 | 0.80 | CDK1 (0.45) | CDK1CCNB1CCNE1CDK2ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11685761-B2 | Cyclic di-nucleotide compounds as sting agonists | MERCK SHARP & DOHME LLC (US) | 2023-06-27 | — | — | US | disclosed |
| US-20220177510-A1 | DERIVATIVES OF GYLCERO-MANNO-HEPTOSE ADP FOR USE IN MODULATING IMMUNE RESPONSE | SHANGHAI YAO YUAN BIOTECHNOLOGY CO LTD (CN) | 2022-06-09 | — | — | US | disclosed |
| US-20210403501-A1 | COMPOSITIONS AND METHODS OF MODULATING THE IMMUNE RESPONSE BY ACTIVATING ALPHA PROTEIN KINASE 1 | SHANGHAI XINQI WU FILM AND TELEVISION INVESTMENT CO., LTD. (CN) | 2021-12-30 | — | — | US | disclosed |
| CN-110461858-A | Acyl nucleosides phosphonate ester, its prodrug and its purposes as drug | UNIV MONTPELLIER | 2019-11-15 | — | — | CN | disclosed |
| WO-2019193533-A1 | 2'2'-CYCLIC DINUCLEOTIDES | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR, V.V.I. (CZ) | 2019-10-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220177510-A1 | DERIVATIVES OF GYLCERO-MANNO-HEPTOSE ADP FOR USE IN MODULATING IMMUNE RESPONSE | GALK1, PHKA1, PGK1 | CDK1 231/4885CCNB1 764/4885CCNE1 920/4885 |
| US-11685761-B2 | Cyclic di-nucleotide compounds as sting agonists | STING1, CGAS, IFNAR1 | CDK1 1548/4885CCNB1 2850/4885CCNE1 2505/4885 |
| US-20210403501-A1 | COMPOSITIONS AND METHODS OF MODULATING THE IMMUNE RESPONSE BY ACTIVATING ALPHA PROTEIN KINASE 1 | PHKA1, PHKA2, PRKCA | CDK1 114/4885CCNB1 634/4885CCNE1 786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.