Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 10/20 | 0.53 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.53 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.53 |
| ▸ | CDK2 | P24941 | 2/20 | 0.53 |
| ▸ | CTSV | O60911 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSH | P09668 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | CASP4 | P49662 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | CTSC | P53634 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | CTSZ | Q9UBR2 | 1/20 | 0.46 |
| ▸ | KLK4 | Q9Y5K2 | 1/20 | 0.46 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12724281 | 0.83 | CDK1 (0.54) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL21451434 | 0.83 | CDK1 (0.71) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL16131580 | 0.80 | PDE4A (0.48) | CDK1CCNB1CCNE1CDK2YTHDC1 | |
| SCHEMBL17450128 | 0.77 | CDK1 (0.60) | CDK1CDK2CTSLYTHDC1ADORA2A | |
| SCHEMBL29141662 | 0.76 | ADORA2A (0.63) | CDK1CCNB1CCNE1CDK2YTHDC1 | |
| SCHEMBL12702671 | 0.76 | PI4KA (0.43) | CDK1CCNE1CDK2YTHDC1ADORA2A | |
| SCHEMBL29100402 | 0.73 | CDK1 (0.49) | CDK1CCNB1CCNE1CDK2CTSV | |
| Hydrochloric Acid SCHEMBL31707879 | 0.73 | CDK1 (0.43) | CDK1CTSVCTSLCTSBCTSH | |
| SCHEMBL24980488 | 0.71 | ADORA2A (0.60) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL26036734 | 0.71 | CDK1 (0.67) | CDK1CCNB1CCNE1CDK2YTHDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110092451-A1 | NUCLEOTIDE ANALOGUES WITH QUATERNARY CARBON STEREOGENIC CENTERS AND METHODS OF USE | INSTITUT DE RECHERCHES CLINIQUES DE MONTREAL (CA) | 2011-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092451-A1 | NUCLEOTIDE ANALOGUES WITH QUATERNARY CARBON STEREOGENIC CENTERS AND METHODS OF USE | NUDT1, NT5C3B, NTPCR | CDK1 1040/4885CCNB1 1212/4885CCNE1 1585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.