SCHEMBL21452297

SCHEMBL21452297

CCCCCCCC/C=C\CCCCCCCCCCCC(=O)C(C)C

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TERT O14746 3/20 0.63
PTPN1 P18031 3/20 0.63
PPARG P37231 3/20 0.63
PPARD Q03181 3/20 0.63
PPARA Q07869 3/20 0.63
CYP1A2 P05177 2/20 0.63
MAPT P10636 2/20 0.63
CYP2C19 P33261 2/20 0.63
BLM P54132 2/20 0.63
HSD17B10 Q99714 2/20 0.63
FABP4 P15090 2/20 0.63
FAAH O00519 2/20 0.63
KMT2A Q03164 2/20 0.63
F7 P08709 2/20 0.63
F3 P13726 2/20 0.63
DUSP3 P51452 2/20 0.63
GMNN O75496 1/20 0.63
USP2 O75604 1/20 0.63
LMNA P02545 1/20 0.63
POLB P06746 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4656721 1.00 TERT (0.63) TERTPTPN1PPARGPPARDPPARA
SCHEMBL21452029 1.00 TERT (0.63) TERTPTPN1PPARGPPARDPPARA
SCHEMBL21451223 1.00 TERT (0.63) TERTPTPN1PPARGPPARDPPARA
SCHEMBL23950440 1.00 TERT (0.63) TERTPTPN1PPARGPPARDPPARA
SCHEMBL23950153 1.00 TERT (0.63) TERTPTPN1PPARGPPARDPPARA
SCHEMBL23950156 1.00 TERT (0.63) TERTPTPN1PPARGPPARDPPARA
SCHEMBL23950132 1.00 TERT (0.63) TERTPTPN1PPARGPPARDPPARA
SCHEMBL23950452 1.00 TERT (0.63) TERTPTPN1PPARGPPARDPPARA
SCHEMBL21448814 1.00 TERT (0.63) TERTPTPN1PPARGPPARDPPARA
SCHEMBL4656717 1.00 TERT (0.63) TERTPTPN1PPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 US disclosed
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 US disclosed
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. 2023-07-20 US disclosed
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. 2023-07-20 US disclosed
US-20210346507-A1 GEMCITABINE PRODRUGS CURE BIOPHARMA INC. 2021-11-11 US disclosed
US-20210323992-A1 GEMCITABINE PRODRUGS CURE BIOPHARMA INC. 2021-10-21 US disclosed
US-20190308988-A1 OPIOID RECEPTOR ANTAGONIST PRODRUGS NIRSUM LABORATORIES, INC. 2019-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS CPT1B, MUSK, MYLK2 TERT 4567/4885PTPN1 3205/4885PPARG 271/4885
US-20210323992-A1 GEMCITABINE PRODRUGS TYMP, PIK3CA, DCK TERT 1681/4885PTPN1 1087/4885PPARG 869/4885
US-20190308988-A1 OPIOID RECEPTOR ANTAGONIST PRODRUGS OPRM1, OPRK1, OPRL1 TERT 4841/4885PTPN1 887/4885PPARG 615/4885
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF MUSK, MYLK2, TNNC1 TERT 4796/4885PTPN1 3843/4885PPARG 498/4885
US-20210346507-A1 GEMCITABINE PRODRUGS TYMP, PIK3CA, DCK TERT 1681/4885PTPN1 1087/4885PPARG 869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.