Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21457085 | 1.00 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2LMNAHPGDKDM4E | |
| SCHEMBL1414224 | 0.82 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2LMNAHPGDKDM4E | |
| SCHEMBL1414225 | 0.82 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2LMNAHPGDKDM4E | |
| SCHEMBL15842643 | 0.78 | CYP2A6 (0.51) | ALDH1A1SMN1; SMN2LMNAHPGDKDM4E | |
| SCHEMBL29849865 | 0.76 | NFE2L2 (0.46) | ALDH1A1SMN1; SMN2LMNAHPGDKDM4E | |
| (Z)-1,2-Diphenylethene SCHEMBL28022680 | 0.76 | CA12 (0.74) | ALDH1A1SMN1; SMN2LMNAHPGDKDM4E | |
| SCHEMBL17384233 | 0.73 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2LMNAHPGDKDM4E | |
| SCHEMBL7118094 | 0.72 | NFE2L2 (0.58) | KDM4EMAOBTRPA1NFE2L2 | |
| SCHEMBL11544222 | 0.72 | NFE2L2 (0.58) | KDM4EMAOBTRPA1NFE2L2 | |
| SCHEMBL11174156 | 0.70 | MTNR1A (0.66) | ALDH1A1SMN1; SMN2LMNAHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3553054-B1 | FLUORESCENT COUMARIN COMPOUNDS AND METHOD OF SYNTHESIS THEREOF | UNIV EVORA (PT) | 2023-01-11 | — | — | EP | disclosed |
| EP-3553054-A1 | FLUORESCENT COUMARIN COMPOUNDS AND METHOD OF SYNTHESIS THEREOF | Universidade de Évora (PT) | 2019-10-16 | — | — | EP | disclosed |