SCHEMBL21458102

SCHEMBL21458102

Cc1sc2ncnc(N[C@H]3CCN(Cc4ccccc4)C3)c2c1C

nearest known ligand 0.88

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.88
HTT P42858 3/20 0.88
SMN1; SMN2 Q16637 3/20 0.88
KMT2A Q03164 3/20 0.88
RAB9A P51151 2/20 0.88
RXFP1 Q9HBX9 2/20 0.88
MAPK1 P28482 2/20 0.88
LMNA P02545 1/20 0.63
NOD2 Q9HC29 1/20 0.63
DRD4 P21917 1/20 0.53
MAPT P10636 2/20 0.52
IRAK4 Q9NWZ3 1/20 0.52
HPGD P15428 1/20 0.49
CYP3A4 P08684 1/20 0.48
NSD2 O96028 1/20 0.47
SCN1A P35498 1/20 0.46
SCN8A Q9UQD0 1/20 0.46
BCHE P06276 2/20 0.46
ACHE P22303 2/20 0.46
BACE1 P56817 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21458104 1.00 MEN1 (0.88) MEN1HTTSMN1; SMN2KMT2ARAB9A
SCHEMBL21458101 1.00 MEN1 (0.88) MEN1HTTSMN1; SMN2KMT2ARAB9A
SCHEMBL12790000 0.94 MEN1 (1.00) MEN1HTTSMN1; SMN2KMT2ARAB9A
SCHEMBL21458107 0.89 MEN1 (0.70) MEN1HTTSMN1; SMN2KMT2ARAB9A
SCHEMBL16090511 0.80 MEN1 (0.74) MEN1HTTSMN1; SMN2KMT2ARAB9A
SCHEMBL18962385 0.79 MEN1 (0.72) MEN1HTTSMN1; SMN2KMT2ARAB9A
SCHEMBL1604211 0.78 MEN1 (0.71) MEN1HTTSMN1; SMN2KMT2ARAB9A
SCHEMBL12710494 0.78 MEN1 (0.71) MEN1HTTSMN1; SMN2KMT2ARAB9A
SCHEMBL1604026 0.77 LMNA (1.00) MEN1HTTSMN1; SMN2KMT2ARAB9A
SCHEMBL19317179 0.77 MEN1 (0.67) MEN1HTTSMN1; SMN2KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12623121-B1 Golf ball TAYLOR MADE GOLF COMPANY, INC. (US) 2026-05-12 US claimed
US-20250152388-A1 NOVEL ENHANCED STENT MAKING METHODS & APPLICATIONS OF THE SAME WITHIN VASCULAR SYSTEM NEEDING THE SAME M4D LLC (US) 2025-05-15 US claimed
CN-222731914-U Rotating shaft structure and electronic product 合肥联宝信息技术有限公司 2025-04-08 CN claimed
CN-118720665-A Manual TIG welding method for high-fragment-rate steel plug welding joint 河南北方红阳机电有限公司 2024-10-01 CN claimed
CN-117957381-A Bearing with seal NTN株式会社 2024-04-30 CN claimed
CN-117925140-A Aircraft tire tread adhesive and preparation method thereof 中国化工集团曙光橡胶工业研究设计院有限公司 2024-04-26 CN claimed
CN-117757744-A Culture medium for enhancing T cell function and dryness and application thereof 中山大学 2024-03-26 CN claimed
CN-115505181-B Aviation tire tread rubber with small mass loss and preparation method and application thereof 中国化工集团曙光橡胶工业研究设计院有限公司 2023-10-20 CN claimed
CN-116874895-A Heat-resistant tread rubber and preparation method and application thereof 中国化工集团曙光橡胶工业研究设计院有限公司 2023-10-13 CN claimed
CN-113801381-B High-performance aviation tire tread rubber and preparation method thereof 中国化工集团曙光橡胶工业研究设计院有限公司 2023-09-12 CN claimed
US-11679111-B2 Fatty acid synthase inhibitors DUKE UNIVERSITY (US) 2023-06-20 US claimed
CN-115505181-A Aircraft tire tread rubber with low mass loss and preparation method and application thereof 中国化工集团曙光橡胶工业研究设计院有限公司 2022-12-23 CN claimed
CN-115386147-A Aircraft tire bead protective rubber and preparation method thereof 中国化工集团曙光橡胶工业研究设计院有限公司 2022-11-25 CN claimed
CN-111944214-B Aircraft tire tread rubber and preparation method and application thereof 中国化工集团曙光橡胶工业研究设计院有限公司 2022-05-03 CN claimed
US-20210338676-A1 FATTY ACID SYNTHASE INHIBITORS DUKE UNIVERSITY (US) 2021-11-04 US claimed
US-20190314376-A1 FATTY ACID SYNTHASE INHIBITORS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2019-10-17 US claimed
US-12623121-B1 Golf ball TAYLOR MADE GOLF COMPANY, INC. (US) 2026-05-12 US disclosed
US-12624226-B2 Drop casting method to form corrosion protective composite layer IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2026-05-12 US disclosed
US-10966981-B2 Fatty acid synthase inhibitors DUKE UNIVERSITY (US) 2021-04-06 US disclosed
US-20190314376-A1 FATTY ACID SYNTHASE INHIBITORS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2019-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624226-B2 Drop casting method to form corrosion protective composite layer LDHA, LDHB, LIFR MEN1 4433/4885HTT 4313/4885SMN1; SMN2 2348/4885
US-12623121-B1 Golf ball ADAMTS4, ADAMTS13, MACF1 MEN1 690/4885HTT 3437/4885SMN1; SMN2 3074/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.