SCHEMBL21472474

SCHEMBL21472474

COCC(=O)N(C)CCCC(C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 1/20 0.31
SLC6A4 P31645 1/20 0.31
BCHE P06276 2/20 0.31
ACHE P22303 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26457713 0.84 CTSK (0.31) SLC6A4
SCHEMBL10110619 0.80 MEN1 (0.34) SLC6A4BCHEACHE
SCHEMBL6097360 0.79 SLC6A4 (0.33) TRPV4SLC6A4BCHEACHE
SCHEMBL21842634 0.79 ALDH1A1 (0.40)
SCHEMBL12793200 0.79 EPHX2 (0.36) BCHEACHE
SCHEMBL12793199 0.79 ALDH1A1 (0.32)
SCHEMBL25615723 0.79 ALDH1A1 (0.35) SLC6A4BCHEACHE
SCHEMBL6097372 0.79 SLC6A4 (0.33) TRPV4SLC6A4BCHEACHE
SCHEMBL21477775 0.77 EPHX2 (0.45)
SCHEMBL8402961 0.76 BCHE (0.37) SLC6A4BCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230130155-A1 MRNAS ENCODING METABOLIC REPROGRAMMING POLYPEPTIDES AND USES THEREOF ARES CAPITAL CORPORATION, AS AGENT 2023-04-27 US disclosed
US-20230130155-A1 MRNAS ENCODING METABOLIC REPROGRAMMING POLYPEPTIDES AND USES THEREOF ARES CAPITAL CORPORATION, AS AGENT 2023-04-27 US disclosed
US-20230027864-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS TO IMMUNE CELLS MODERNATX, INC. 2023-01-26 US disclosed
US-20190314291-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS TO IMMUNE CELLS MODERNATX, INC. 2019-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230027864-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS TO IMMUNE CELLS LCP2, CD14, MYD88 TRPV4 3163/4885SLC6A4 3913/4885BCHE 4024/4885
US-20230130155-A1 MRNAS ENCODING METABOLIC REPROGRAMMING POLYPEPTIDES AND USES THEREOF HMOX1, CD209, HMOX2 TRPV4 2821/4885SLC6A4 3869/4885BCHE 3973/4885
US-20190314291-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF AGENTS TO IMMUNE CELLS LCP2, CD14, MYD88 TRPV4 3163/4885SLC6A4 3913/4885BCHE 4024/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.