Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5271914 | 0.91 | — | — | |
| SCHEMBL28919270 | 0.88 | OPRM1 (0.50) | OPRM1ALDH1A1TDP1TP53 | |
| SCHEMBL17722707 | 0.81 | PIK3CD (0.38) | ALDH1A1 | |
| SCHEMBL7947743 | 0.81 | OPRM1 (0.50) | OPRM1ALDH1A1TDP1TP53 | |
| SCHEMBL18403007 | 0.79 | HTT (0.31) | — | |
| SCHEMBL21501036 | 0.78 | OPRM1 (0.38) | OPRM1ALDH1A1TDP1TP53 | |
| SCHEMBL24543339 | 0.77 | OPRM1 (0.36) | OPRM1ALDH1A1TDP1 | |
| SCHEMBL12702655 | 0.77 | OPRM1 (0.41) | OPRM1ALDH1A1TDP1TP53 | |
| SCHEMBL11477603 | 0.77 | OPRM1 (0.58) | OPRM1ALDH1A1TDP1TP53 | |
| SCHEMBL117963 | 0.77 | ALDH1A1 (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10550136-B2 | Method for producing polyalkylene glycol derivative having amino group at end | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2020-02-04 | — | — | US | disclosed |
| US-20190315777-A1 | METHOD FOR PRODUCING POLYALKYLENE GLYCOL DERIVATIVE HAVING AMINO GROUP AT END | SHINETSU CHEMICAL CO (JP) | 2019-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10550136-B2 | Method for producing polyalkylene glycol derivative having amino group at end | RAD1, AP3B1, RER1 | OPRM1 670/4885ALDH1A1 282/4885TDP1 2792/4885 |
| US-20190315777-A1 | METHOD FOR PRODUCING POLYALKYLENE GLYCOL DERIVATIVE HAVING AMINO GROUP AT END | KCNMA1, KCNMB1, KCNMB4 | OPRM1 473/4885ALDH1A1 319/4885TDP1 3022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.