Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13881046 | 0.88 | PDK1 (0.41) | POLBAPPSMN1; SMN2ALOX15ALOX12 | |
| SCHEMBL4044685 | 0.87 | PDK1 (0.40) | POLBSMN1; SMN2ALOX15ALOX12VCAM1 | |
| SCHEMBL13498001 | 0.86 | KAT2B (0.42) | APPSMN1; SMN2ALOX15ALOX12VCAM1 | |
| SCHEMBL13179034 | 0.85 | GSR (0.41) | POLBAPPSMN1; SMN2VCAM1MAPT | |
| SCHEMBL27705588 | 0.85 | PTGS1 (0.37) | POLBSMN1; SMN2ALOX15ALOX12TSHR | |
| SCHEMBL2148284 | 0.84 | LOXL2 (0.43) | APPALOX15ALOX12VCAM1CYP3A4 | |
| SCHEMBL13888388 | 0.84 | APP (0.38) | APPALOX15ALOX12VCAM1CYP3A4 | |
| SCHEMBL16281668 | 0.82 | APP (0.41) | APPALOX15ALOX12VCAM1CYP3A4 | |
| SCHEMBL27705591 | 0.82 | CYP3A4 (0.34) | POLBSMN1; SMN2ALOX15ALOX12VCAM1 | |
| SCHEMBL26979837 | 0.80 | TSHR (0.40) | POLBSMN1; SMN2ALOX15ALOX12CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080227742-A1 | Photocleavable oligonucleotide and uses thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-09-18 | — | — | US | claimed |
| US-20250215040-A1 | METHOD AND COMPOUND | ATDBio Limited (GB) | 2025-07-03 | — | — | US | disclosed |
| US-20250042932-A1 | METHOD FOR PRODUCING POLYNUCLEOTIDES | ATDBio Limited (GB) | 2025-02-06 | — | — | US | disclosed |
| CN-119173522-A | Methods and compounds | ATD生物有限公司 | 2024-12-20 | — | — | CN | disclosed |
| CN-118339173-A | Method for preparing polynucleotide | ATD生物有限公司 | 2024-07-12 | — | — | CN | disclosed |
| WO-2023180237-A1 | METHOD AND COMPOUND | ATDBio Limited (GB) | 2023-09-28 | — | — | WO | disclosed |
| EP-4249495-A1 | METHOD FOR THE PURIFICATION OF POLYNUCLEOTIDES AND ANALOGUES THEREOF | ATDBio Limited (GB) | 2023-09-27 | — | — | EP | disclosed |
| WO-2023099471-A1 | METHOD FOR PRODUCING POLYNUCLEOTIDES | ATDBio Limited (GB) | 2023-06-08 | — | — | WO | disclosed |
| EP-4186914-A1 | METHOD FOR PRODUCING POLYNUCLEOTIDES | ATDBio Limited (GB) | 2023-05-31 | — | — | EP | disclosed |
| EP-4186914-A1 | METHOD FOR PRODUCING POLYNUCLEOTIDES | ATDBio Limited (GB) | 2023-05-31 | — | — | EP | disclosed |
| CN-101184996-A | Electrochemical detection method | INVERNESS MEDICAL SWITZERLAND (CH) | 2008-05-21 | — | — | CN | disclosed |
| EP-1866645-A2 | ELECTROCHEMICAL ASSAY | Inverness Medical Switzerland GmbH (CH) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006103450-A2 | ELECTROCHEMICAL ASSAY | INVERNESS MEDICAL SWITZERLAND GMBH (CH) | 2006-10-05 | — | — | WO | disclosed |
| WO-2004019000-A2 | CHEMICAL REAGENTS AND METHODS FOR DETECTION AND QUANTIFICATION OF PROTEINS IN COMPLEX MIXTURES | THE INSTITUTE FOR SYSTEMS BIOLOGY (US) | 2004-03-04 | — | — | WO | disclosed |
| US-20040038319-A1 | Chemical reagents and methods for detection and quantification of proteins in complex mixtures | INSTITUTE FOR SYSTEMS BIOLOGY, THE | 2004-02-26 | — | — | US | disclosed |
| EP-0185762-B1 | CELL-DELIVERY AGENT | DANA-FARBER CANCER INSTITUTE, INC. (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0185762-A4 | CELL-DELIVERY AGENT. | DANA FARBER CANCER INST INC (US) | 1986-12-01 | — | — | EP | disclosed |
| US-4625014-A | Cell-delivery agent | DANA-FARBER CANCER INSTITUTE, INC. (US) | 1986-11-25 | — | — | US | disclosed |
| EP-0185762-A1 | CELL-DELIVERY AGENT. | DANA FARBER CANCER INST INC (US) | 1986-07-02 | — | — | EP | disclosed |
| WO-1986000527-A1 | CELL-DELIVERY AGENT | DANA-FARBER CANCER INSTITUTE, INC. (US) | 1986-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040038319-A1 | Chemical reagents and methods for detection and quantification of proteins in complex mixtures | STUB1, INHA, IAPP | POLB 3240/4885APP 39/4885SMN1; SMN2 2687/4885 |
| US-20250042932-A1 | METHOD FOR PRODUCING POLYNUCLEOTIDES | POLN, RNGTT, PNP | POLB 15/4885APP 1274/4885SMN1; SMN2 292/4885 |
| US-20250215040-A1 | METHOD AND COMPOUND | POLN, POLRMT, FBL | POLB 23/4885APP 2575/4885SMN1; SMN2 89/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.