Benzimidazole

Benzimidazole

SCHEMBL2148679

c1c[nH]cn1.c1ccc2[nH]cnc2c1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
FKBP5 Q13451 1/20 0.46
QPCT Q16769 3/20 0.41
QPCTL Q9NXS2 3/20 0.41
KDM4E B2RXH2 5/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
HPGD P15428 3/20 0.40
RAB9A P51151 2/20 0.40
NPC1 O15118 1/20 0.40
TP53 P04637 1/20 0.40
GAA P10253 2/20 0.38
PRKCI P41743 2/20 0.38
APOBEC3G Q9HC16 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
PDPK1 O15530 1/20 0.38
CA12 O43570 1/20 0.38
PARP1 P09874 1/20 0.38
ALOX15 P16050 1/20 0.38
CA9 Q16790 1/20 0.38
TNKS2 Q9H2K2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzimidazole SCHEMBL28288033 1.00 ALDH1A1 (0.46) ALDH1A1FKBP5QPCTQPCTLKDM4E
Indole SCHEMBL21495202 0.89 TRPA1 (0.49) ALDH1A1FKBP5QPCTQPCTLKDM4E
Isoquinoline SCHEMBL29058634 0.87 QPCT (0.39) ALDH1A1FKBP5QPCTQPCTLKDM4E
Benzimidazole SCHEMBL27880765 0.83 QPCT (0.46) ALDH1A1QPCTQPCTLKDM4ESMN1; SMN2
Benzimidazole SCHEMBL28471263 0.82 SMN1; SMN2 (0.47) ALDH1A1QPCTQPCTLKDM4ESMN1; SMN2
Benzimidazole SCHEMBL28472447 0.82 SMN1; SMN2 (0.47) ALDH1A1QPCTQPCTLKDM4ESMN1; SMN2
Benzimidazole SCHEMBL5133620 0.82 SMN1; SMN2 (0.47) ALDH1A1QPCTQPCTLKDM4ESMN1; SMN2
Benzimidazole SCHEMBL4894704 0.82 SMN1; SMN2 (0.47) ALDH1A1QPCTQPCTLKDM4ESMN1; SMN2
Benzimidazole SCHEMBL28467045 0.82 SMN1; SMN2 (0.47) ALDH1A1QPCTQPCTLKDM4ESMN1; SMN2
Benzimidazole SCHEMBL461969 0.82 SMN1; SMN2 (0.50) ALDH1A1QPCTQPCTLKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117362326-A Organic boron compound containing benzimidazole imidazole, and preparation method and application thereof 中国科学院长春应用化学研究所 2024-01-09 CN claimed
WO-2017168451-A1 DERIVATIVES OF IMIDAZOLE AND BENZIMIDAZOLE, METHOD OF PREPARATION AND USE THEREOF SHIV NADAR UNIVERSITY (IN) 2017-10-05 WO claimed
CN-1692180-A Composite material and composite film UNIV STUTTGART (DE) 2005-11-02 CN claimed
EP-0888369-A1 SIALYL LEWIS X MIMETICS CONTAINING FLAVANOID BACKBONES GLYCOMED INCORPORATED (US) 1999-01-07 EP claimed
WO-1997031007-A1 SIALYL LEWISx MIMETICS CONTAINING FLAVANOID BACKBONES GLYCOMED INCORPORATED (US) 1997-08-28 WO claimed
JP-8050341-A None JP disclosed
CN-117362326-A Organic boron compound containing benzimidazole imidazole, and preparation method and application thereof 中国科学院长春应用化学研究所 2024-01-09 CN disclosed
CN-117362326-A Organic boron compound containing benzimidazole imidazole, and preparation method and application thereof 中国科学院长春应用化学研究所 2024-01-09 CN disclosed
CN-117362326-A Organic boron compound containing benzimidazole imidazole, and preparation method and application thereof 中国科学院长春应用化学研究所 2024-01-09 CN disclosed
US-20230299242-A1 LIGHT EMITTING DEVICES AND USES THEREOF IN DISPLAYS Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) 2023-09-21 US disclosed
EP-4230708-A1 LIGHT-EMITTING DEVICE AND USE THEREOF IN DISPLAY Zhejiang Brilliant Optoelectronic Technology Co., Ltd. (CN) 2023-08-23 EP disclosed
CN-115915635-A Circuit board high-compactness protective film surface treatment method and circuit board 盐城市贝加尔电子材料有限公司 2023-04-04 CN disclosed
EP-0465078-B1 Infra-red sensitive photographic materials MINNESOTA MINING & MFG (US) 1995-06-28 EP disclosed
US-5216166-A Cyanine dye with nitro group substituent MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-06-01 US disclosed
EP-0283041-B1 DIRECT POSITIVE SILVER HALIDE PHOTOSENSITIVE MATERIAL AND METHOD FOR FORMING DIRECT POSITIVE IMAGE FUJI PHOTO FILM CO., LTD. (JP) 1992-10-07 EP disclosed
EP-0465078-A1 Infra-red sensitive photographic materials MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-01-08 EP disclosed
CN-1045907-A Improve the insecticides of effect CIBA GEIGY AG (CH) 1990-10-10 CN disclosed
US-4952483-A NOVEL HYDRAZINE NUCLEATING AGENTS AND ACCELERATORS FUJI PHOTO FILM CO., LTD. (JP) 1990-08-28 US disclosed
EP-0283041-A1 Direct positive silver halide photosensitive material and method for forming direct positive image FUJI PHOTO FILM CO., LTD. (JP) 1988-09-21 EP disclosed
EP-0056977-B1 IMMUNE ADSORBENT, ADSORBING DEVICE AND BLOOD PURIFYING APPARATUS Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1985-05-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230299242-A1 LIGHT EMITTING DEVICES AND USES THEREOF IN DISPLAYS ALDH1A2, CRY1, ALDH1A3 ALDH1A1 9/4885FKBP5 1091/4885QPCT 4365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.