SCHEMBL2149501

SCHEMBL2149501

O=C(O)c1ccc(F)c(S)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.48
MAPK1 P28482 1/20 0.48
HTT P42858 1/20 0.48
RAB9A P51151 1/20 0.48
TSHR P16473 3/20 0.46
TP53 P04637 1/20 0.46
KDM4E B2RXH2 3/20 0.45
GAA P10253 2/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
POLB P06746 1/20 0.45
MAPT P10636 1/20 0.45
CA4 P22748 1/20 0.45
CA6 P23280 1/20 0.45
PTGS2 P35354 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45
CA14 Q9ULX7 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13354032 0.84 CES2 (0.46) LMNAHTTTSHRMAPTL3MBTL1
SCHEMBL8403465 0.84 LMNA (0.55) LMNAMAPK1HTTRAB9ATSHR
SCHEMBL21383062 0.81 TSHR (0.55) MAPK1TSHRTP53KDM4EGAA
SCHEMBL27151 0.79 CES2 (0.70) LMNAMAPK1HTTRAB9ATSHR
SCHEMBL29349680 0.79 CES2 (0.70) LMNAMAPK1HTTRAB9ATSHR
SCHEMBL28368751 0.78 LTA4H (0.50) LMNAMAPK1RAB9ATSHRTP53
Hydrochloric Acid SCHEMBL31439055 0.77 CES2 (0.67) LMNAMAPK1HTTRAB9ATSHR
Hydrochloric Acid SCHEMBL10557218 0.77 CES2 (0.67) LMNAMAPK1HTTRAB9ATSHR
Hydrochloric Acid SCHEMBL31439035 0.77 CES2 (0.67) LMNAMAPK1HTTRAB9ATSHR
SCHEMBL22926190 0.76 HDAC6 (0.47) HTTTSHRGAACA2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3859804-B1 SEMICONDUCTOR DEVICE HAVING QUANTUM DOTS CANON KK (JP) 2024-08-07 EP claimed
US-12245446-B2 Semiconductor device having quantum dots, display device, imaging system, and moving body CANON KABUSHIKI KAISHA (JP) 2025-03-04 US disclosed
EP-3859804-B1 SEMICONDUCTOR DEVICE HAVING QUANTUM DOTS CANON KK (JP) 2024-08-07 EP disclosed
CN-113285024-A Semiconductor device having quantum dots, display device, imaging system, and moving object 佳能株式会社 2021-08-20 CN disclosed
US-20210242416-A1 SEMICONDUCTOR DEVICE HAVING QUANTUM DOTS, DISPLAY DEVICE, IMAGING SYSTEM, AND MOVING BODY CANON KABUSHIKI KAISHA (JP) 2021-08-05 US disclosed
EP-3859804-A2 SEMICONDUCTOR DEVICE HAVING QUANTUM DOTS CANON KABUSHIKI KAISHA (JP) 2021-08-04 EP disclosed
US-10710959-B2 Sulfide alkyl compounds for HBV treatment NOVIRA THERAPEUTICS, INC. (US) 2020-07-14 US disclosed
US-10710959-B2 Sulfide alkyl compounds for HBV treatment NOVIRA THERAPEUTICS, INC. (US) 2020-07-14 US disclosed
EP-3227262-B1 SULFIDE ALKYL AND PYRIDYL REVERSE SULFONAMIDE COMPOUNDS FOR HBV TREATMENT NOVIRA THERAPEUTICS INC (US) 2020-05-13 EP disclosed
EP-3227262-B1 SULFIDE ALKYL AND PYRIDYL REVERSE SULFONAMIDE COMPOUNDS FOR HBV TREATMENT NOVIRA THERAPEUTICS INC (US) 2020-05-13 EP disclosed
US-9597332-B2 Sulfide alkyl compounds for HBV treatment NOVIRA THERAPEUTICS, INC. (US) 2017-03-21 US disclosed
US-9597332-B2 Sulfide alkyl compounds for HBV treatment NOVIRA THERAPEUTICS, INC. (US) 2017-03-21 US disclosed
US-9597332-B2 Sulfide alkyl compounds for HBV treatment NOVIRA THERAPEUTICS, INC. (US) 2017-03-21 US disclosed
WO-2016089990-A1 SULFIDE ALKYL AND PYRIDYL REVERSE SULFONAMIDE COMPOUNDS FOR HBV TREATMENT NOVIRA THERAPEUTICS, INC. (US) 2016-06-09 WO disclosed
US-20160151375-A1 SULFIDE ALKYL COMPOUNDS FOR HBV TREATMENT NOVIRA THERAPEUTICS, INC. 2016-06-02 US disclosed
US-20160151375-A1 SULFIDE ALKYL COMPOUNDS FOR HBV TREATMENT NOVIRA THERAPEUTICS, INC. 2016-06-02 US disclosed
US-20160151375-A1 SULFIDE ALKYL COMPOUNDS FOR HBV TREATMENT NOVIRA THERAPEUTICS, INC. 2016-06-02 US disclosed
US-20110230403-A1 GLYCOSIDE DERIVATIVES AND USES THEREOF NOVARTIS AG (CH) 2011-09-22 US disclosed
EP-2342187-A1 GLYCOSIDE DERIVATIVES AND USES THEREOF Novartis AG (CH) 2011-07-13 EP disclosed
WO-2010031813-A1 GLYCOSIDE DERIVATIVES AND USES THEREOF NOVARTIS AG (CH) 2010-03-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160151375-A1 SULFIDE ALKYL COMPOUNDS FOR HBV TREATMENT HAVCR2, HCCS, CBS LMNA 4148/4885MAPK1 3024/4885HTT 4014/4885
US-20110230403-A1 GLYCOSIDE DERIVATIVES AND USES THEREOF SLC5A1, SLC5A2, HSD17B14 LMNA 2362/4885MAPK1 1587/4885HTT 2300/4885
US-10710959-B2 Sulfide alkyl compounds for HBV treatment HAVCR2, HCCS, CBS LMNA 4148/4885MAPK1 3024/4885HTT 4014/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.