Indole

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30011	0.92	MAPT (0.54)	AHRMAPTCYP3A4LMNAALOX15
	SCHEMBL29904251	0.92	MAPT (0.54)	AHRMAPTCYP3A4LMNAALOX15
	Pyrimidine SCHEMBL28222787	0.84	MAPT (0.49)	MAPTCYP3A4LMNAALOX15NOS1
	Quinoline SCHEMBL28248827	0.83	MAPT (0.48)	MAPTCYP3A4LMNAALOX15NOS1
	SCHEMBL21496937	0.83	ALDH1A1 (0.48)	MAPTCYP3A4LMNAALOX15NOS1
	4-Nitrotoluene SCHEMBL27922522	0.83	ACHE (0.56)	TRPA1CA1CA2ITGB2ICAM1
	SCHEMBL30597526	0.81	MAPT (0.54)	CA1CA2AHRMAPTCYP3A4
	SCHEMBL28686	0.81	MAPT (0.54)	CA1CA2AHRMAPTCYP3A4
	Indole SCHEMBL28798242	0.80	TRPA1 (0.50)	TRPA1CA1CA2ITGB2ICAM1
	3-Nitrobenzaldehyde SCHEMBL27857158	0.80	NFE2L2 (0.50)	TRPA1CA1CA2ITGB2ICAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.