Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21495178 | 0.87 | SMN1; SMN2 (0.35) | MAPTSMN1; SMN2MEN1ALDH1A1TSHR | |
| SCHEMBL21500715 | 0.77 | SMN1; SMN2 (0.42) | MAPTSMN1; SMN2ALDH1A1KMT2AGAA | |
| SCHEMBL21495180 | 0.77 | MTNR1A (0.32) | ALDH1A1GAAMTNR1AMTNR1BADRA2A | |
| SCHEMBL3190996 | 0.72 | MAOA (0.37) | MAPTSMN1; SMN2MEN1ALDH1A1TSHR | |
| SCHEMBL30392289 | 0.72 | MAOA (0.37) | MAPTSMN1; SMN2MEN1ALDH1A1TSHR | |
| SCHEMBL10033616 | 0.69 | FFAR4 (0.37) | MAPTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL14390906 | 0.69 | ALOX15 (0.38) | MAPTSMN1; SMN2MEN1HTTKMT2A | |
| SCHEMBL8442813 | 0.68 | MAPT (0.67) | MAPTSMN1; SMN2MEN1ALDH1A1TSHR | |
| SCHEMBL21500712 | 0.67 | ALOX5 (0.31) | RAB9A | |
| SCHEMBL15628793 | 0.67 | ALDH1A1 (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019202140-A1 | PROCESS FOR DYEING KERATIN FIBRES COMPRISING THE APPLICATION OF A CHROMENOL/CHROMEN-2-ONE DERIVATIVE, COMPOSITION AND DEVICE | L'OREAL (FR) | 2019-10-24 | — | — | WO | disclosed |