Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 5/20 | 0.37 |
| ▸ | CNR1 | P21554 | 4/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17780834 | 0.95 | ALDH1A1 (0.42) | TSHRALDH1A1CNR2CNR1ACHE | |
| SCHEMBL22336635 | 0.88 | ALDH1A1 (0.42) | TSHRALDH1A1CNR2CNR1ACHE | |
| SCHEMBL6353251 | 0.83 | CES2 (0.48) | TSHRALDH1A1CNR2CNR1ACHE | |
| SCHEMBL8469732 | 0.83 | CES2 (0.48) | TSHRALDH1A1CNR2CNR1ACHE | |
| SCHEMBL313428 | 0.83 | ALDH1A1 (0.52) | TSHRALDH1A1ACHETDP1KDM4E | |
| SCHEMBL16318397 | 0.81 | HTR3E (0.44) | TSHRALDH1A1MAPTTP53HCRTR2 | |
| SCHEMBL615437 | 0.80 | ALDH1A1 (0.61) | TSHRALDH1A1ACHETDP1KDM4E | |
| SCHEMBL16982395 | 0.80 | ALDH1A1 (0.61) | TSHRALDH1A1ACHETDP1KDM4E | |
| SCHEMBL6123161 | 0.80 | ALDH1A1 (0.61) | TSHRALDH1A1ACHETDP1KDM4E | |
| SCHEMBL12240222 | 0.80 | ALDH1A1 (0.61) | TSHRALDH1A1ACHETDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8029920-B2 | 1,3,5-tris(diarylamino)benzenes and use thereof | BANDO CHEMICAL INDUSTRIES, LTD (JP) | 2011-10-04 | — | — | US | disclosed |
| US-8029920-B2 | 1,3,5-tris(diarylamino)benzenes and use thereof | BANDO CHEMICAL INDUSTRIES, LTD (JP) | 2011-10-04 | — | — | US | disclosed |
| US-8029920-B2 | 1,3,5-tris(diarylamino)benzenes and use thereof | BANDO CHEMICAL INDUSTRIES, LTD (JP) | 2011-10-04 | — | — | US | disclosed |
| EP-1995235-B1 | NOVEL 1,3,5-TRIS(DIARYLAMINO)BENZENES AND USE THEREOF | BANDO CHEMICAL IND (JP) | 2011-09-14 | — | — | EP | disclosed |
| EP-1995235-B1 | NOVEL 1,3,5-TRIS(DIARYLAMINO)BENZENES AND USE THEREOF | BANDO CHEMICAL IND (JP) | 2011-09-14 | — | — | EP | disclosed |
| US-20110186834-A1 | NOVEL 1,3,5-TRIS(DIARYLAMINO)BENZENE AND USE THEREOF | BANDO CHEMICAL INDUSTRIES, LTD. (JP) | 2011-08-04 | — | — | US | disclosed |
| US-20110186834-A1 | NOVEL 1,3,5-TRIS(DIARYLAMINO)BENZENE AND USE THEREOF | BANDO CHEMICAL INDUSTRIES, LTD. (JP) | 2011-08-04 | — | — | US | disclosed |
| US-20110186834-A1 | NOVEL 1,3,5-TRIS(DIARYLAMINO)BENZENE AND USE THEREOF | BANDO CHEMICAL INDUSTRIES, LTD. (JP) | 2011-08-04 | — | — | US | disclosed |
| EP-2341043-A1 | NOVEL 1,3,5-TRIS(DIARYLAMINO)BENZENE AND USE THEREOF | Bando Chemical Industries, Ltd. (JP) | 2011-07-06 | — | — | EP | disclosed |
| EP-2341043-A1 | NOVEL 1,3,5-TRIS(DIARYLAMINO)BENZENE AND USE THEREOF | Bando Chemical Industries, Ltd. (JP) | 2011-07-06 | — | — | EP | disclosed |
| US-20090058287-A1 | NOVEL 1,3,5-TRIS(DIARYLAMINO)BENZENES AND USE THEREOF | BANDO CHEMICAL INDUSTRIES, LTD. (JP) | 2009-03-05 | — | — | US | disclosed |
| US-20090058287-A1 | NOVEL 1,3,5-TRIS(DIARYLAMINO)BENZENES AND USE THEREOF | BANDO CHEMICAL INDUSTRIES, LTD. (JP) | 2009-03-05 | — | — | US | disclosed |
| US-20090058287-A1 | NOVEL 1,3,5-TRIS(DIARYLAMINO)BENZENES AND USE THEREOF | BANDO CHEMICAL INDUSTRIES, LTD. (JP) | 2009-03-05 | — | — | US | disclosed |
| EP-1995235-A1 | NOVEL 1,3,5-TRIS(DIARYLAMINO)BENZENES AND USE THEREOF | BANDO CHEMICAL INDUSTRIES, LTD. (JP) | 2008-11-26 | — | — | EP | disclosed |
| EP-1995235-A1 | NOVEL 1,3,5-TRIS(DIARYLAMINO)BENZENES AND USE THEREOF | BANDO CHEMICAL INDUSTRIES, LTD. (JP) | 2008-11-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110186834-A1 | NOVEL 1,3,5-TRIS(DIARYLAMINO)BENZENE AND USE THEREOF | CBR1, CYP1B1, CBR3 | TSHR 2233/4885ALDH1A1 418/4885CNR2 17/4885 |
| US-20090058287-A1 | NOVEL 1,3,5-TRIS(DIARYLAMINO)BENZENES AND USE THEREOF | TMBIM6, TNPO1, CACNA1I | TSHR 4439/4885ALDH1A1 2458/4885CNR2 913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.