Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 4/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6353251 | 1.00 | CES2 (0.48) | CES2CES1ALDH1A1TSHRLMNA | |
| SCHEMBL26306350 | 0.93 | NPSR1 (0.44) | CES2CES1ALDH1A1TSHRLMNA | |
| SCHEMBL20059332 | 0.91 | ALDH1A1 (0.46) | CES2CES1ALDH1A1TSHRLMNA | |
| SCHEMBL8187096 | 0.87 | MAOA (0.50) | CES2CES1ALDH1A1KDM4EMAPT | |
| SCHEMBL14526489 | 0.87 | MAOA (0.50) | CES2CES1ALDH1A1KDM4EMAPT | |
| SCHEMBL6123161 | 0.86 | ALDH1A1 (0.61) | ALDH1A1TSHRLMNAKDM4EMAPT | |
| SCHEMBL666720 | 0.86 | LMNA (0.57) | CES2CES1ALDH1A1TSHRLMNA | |
| SCHEMBL16982395 | 0.86 | ALDH1A1 (0.61) | ALDH1A1TSHRLMNAKDM4EMAPT | |
| SCHEMBL7486403 | 0.86 | ALDH1A1 (0.61) | ALDH1A1TSHRLMNAKDM4EMAPT | |
| SCHEMBL12240222 | 0.86 | ALDH1A1 (0.61) | ALDH1A1TSHRLMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5999780-A | Controllably conductive polymer compositions for development systems | XEROX CORPORATION (US) | 1999-12-07 | — | — | US | claimed |
| US-5834080-A | Controllably conductive polymer compositions for development systems | XEROX CORPORATION (US) | 1998-11-10 | — | — | US | claimed |
| US-10032989-B2 | Spirobifluorene derivative-based materials for electronic devices | MERCK PATENT GMBH (DE) | 2018-07-24 | — | — | US | disclosed |
| US-10032989-B2 | Spirobifluorene derivative-based materials for electronic devices | MERCK PATENT GMBH (DE) | 2018-07-24 | — | — | US | disclosed |
| US-20180026188-A1 | SPIROBIFLUORENE DERIVATIVE-BASED MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| US-20180026188-A1 | SPIROBIFLUORENE DERIVATIVE-BASED MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| WO-2016131521-A1 | SPIROBIFLUORENE DERIVATIVE-BASED MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-08-25 | — | — | WO | disclosed |
| US-5999780-A | Controllably conductive polymer compositions for development systems | XEROX CORPORATION (US) | 1999-12-07 | — | — | US | disclosed |
| US-5834080-A | Controllably conductive polymer compositions for development systems | XEROX CORPORATION (US) | 1998-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180026188-A1 | SPIROBIFLUORENE DERIVATIVE-BASED MATERIALS FOR ELECTRONIC DEVICES | SDHB, SDHA, PKD1 | CES2 1665/4885CES1 4484/4885ALDH1A1 107/4885 |
| US-10032989-B2 | Spirobifluorene derivative-based materials for electronic devices | SDHB, SDHA, PKD1 | CES2 1665/4885CES1 4484/4885ALDH1A1 107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.