Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | MMP1 | P03956 | 1/20 | 0.66 |
| ▸ | MMP2 | P08253 | 1/20 | 0.66 |
| ▸ | MMP9 | P14780 | 1/20 | 0.66 |
| ▸ | MMP8 | P22894 | 1/20 | 0.66 |
| ▸ | MMP13 | P45452 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2153154 | 0.88 | MMP1 (0.75) | MEN1KMT2AMMP1MMP2MMP9 | |
| SCHEMBL1542223 | 0.80 | PKM (0.63) | MEN1KMT2AMMP1MMP2MMP9 | |
| SCHEMBL11068063 | 0.79 | KMT2A (0.74) | MEN1KMT2AALDH1A1HPGDGAA | |
| SCHEMBL11060904 | 0.77 | KMT2A (0.73) | MEN1KMT2AALDH1A1HPGDGAA | |
| SCHEMBL6995692 | 0.76 | KMT2A (0.67) | MEN1KMT2AALDH1A1HPGDGAA | |
| SCHEMBL1083633 | 0.76 | MEN1 (0.77) | MEN1KMT2AALDH1A1HPGDGAA | |
| SCHEMBL3887061 | 0.74 | MEN1 (0.71) | MEN1KMT2AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6967304 | 0.73 | ALDH1A1 (0.93) | MEN1KMT2AALDH1A1HPGDGAA | |
| SCHEMBL2153304 | 0.73 | ALDH1A1 (0.74) | MEN1KMT2AMMP1MMP2MMP9 | |
| SCHEMBL2153021 | 0.73 | ALDH1A1 (0.70) | MEN1KMT2AMMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120295890-A1 | GLYCOSAMINOGLYCAN INHIBITORS | Zacharon Pharmaceutical, Inc. (US) | 2012-11-22 | — | — | US | disclosed |
| WO-2011082175-A2 | GLYCOSAMINOGLYCAN INHIBITORS | ZACHARON PHARMACEUTICALS, INC. (US) | 2011-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295890-A1 | GLYCOSAMINOGLYCAN INHIBITORS | CSGALNACT1, FUT5, ST3GAL3 | MEN1 4634/4885KMT2A 4294/4885MMP1 233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.