Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL167878 | 0.86 | ALDH1A1 (0.67) | PKMHTTALDH1A1ALOX12NPSR1 | |
| SCHEMBL5450556 | 0.82 | ALDH1A1 (0.70) | HTTALDH1A1ALOX12NPSR1L3MBTL1 | |
| SCHEMBL2153255 | 0.80 | MEN1 (0.66) | HTTALDH1A1ALOX12NPSR1L3MBTL1 | |
| SCHEMBL2153304 | 0.77 | ALDH1A1 (0.74) | HTTALDH1A1ALOX12NPSR1L3MBTL1 | |
| SCHEMBL2153021 | 0.77 | ALDH1A1 (0.70) | HTTALDH1A1ALOX12NPSR1L3MBTL1 | |
| SCHEMBL12839889 | 0.76 | ALDH1A1 (0.68) | HTTALDH1A1ALOX12NPSR1L3MBTL1 | |
| SCHEMBL11064749 | 0.74 | PKM (0.67) | PKMALDH1A1L3MBTL1KDM4E | |
| SCHEMBL12467306 | 0.74 | ALDH1A1 (0.72) | PKMHTTALDH1A1ALOX12NPSR1 | |
| SCHEMBL2153154 | 0.74 | MMP1 (0.75) | HTTALDH1A1ALOX12NPSR1L3MBTL1 | |
| SCHEMBL2153243 | 0.74 | ALDH1A1 (1.00) | HTTALDH1A1ALOX12NPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120295890-A1 | GLYCOSAMINOGLYCAN INHIBITORS | Zacharon Pharmaceutical, Inc. (US) | 2012-11-22 | — | — | US | disclosed |
| WO-2011082175-A2 | GLYCOSAMINOGLYCAN INHIBITORS | ZACHARON PHARMACEUTICALS, INC. (US) | 2011-07-07 | — | — | WO | disclosed |
| EP-2307440-A2 | HEPARAN SULFATE INHIBITORS | Zacharon Pharmaceuticals, Inc. (US) | 2011-04-13 | — | — | EP | disclosed |
| US-20100048638-A1 | HEPARAN SULFATE INHIBITORS | ZACHARON PHARMACEUTICALS, INC. (US) | 2010-02-25 | — | — | US | disclosed |
| US-20100048638-A1 | HEPARAN SULFATE INHIBITORS | ZACHARON PHARMACEUTICALS, INC. (US) | 2010-02-25 | — | — | US | disclosed |
| US-20100048638-A1 | HEPARAN SULFATE INHIBITORS | ZACHARON PHARMACEUTICALS, INC. (US) | 2010-02-25 | — | — | US | disclosed |
| WO-2010003023-A2 | HEPARAN SULFATE INHIBITORS | ZACHARON PHARMACEUTICALS, INC. (US) | 2010-01-07 | — | — | WO | disclosed |
| WO-2010003023-A2 | HEPARAN SULFATE INHIBITORS | ZACHARON PHARMACEUTICALS, INC. (US) | 2010-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295890-A1 | GLYCOSAMINOGLYCAN INHIBITORS | CSGALNACT1, FUT5, ST3GAL3 | PKM 4578/4885KCNH2 4867/4885HTT 2106/4885 |
| US-20100048638-A1 | HEPARAN SULFATE INHIBITORS | HPSE, ENGASE, CSGALNACT1 | PKM 3376/4885KCNH2 4843/4885HTT 806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.